Results 11 to 20 of about 2,789,846 (387)

Morphology and gene expression profiling provide complementary information for mapping cell state

bioRxiv, 2022
Morphological and gene expression profiling can cost-effectively capture thousands of features in thousands of samples across perturbations by disease, mutation, or drug treatments, but it is unclear to what extent the two modalities capture overlapping ...
G. Way, Ted E. Natoli, Adeniyi Adeboye, Lev Litichevskiy, Andrew Yang, Xiaodong Lu, Juan C. Caicedo, B. Cimini, Kyle W. Karhohs, David J. Logan, M. Rohban, M. Kost-Alimova, K. Hartland, Michael Bornholdt, Niranjana Chandrasekaran, Marzieh Haghighi, Shantanu Singh, A. Subramanian, Anne E Carpenter   +18 more
semanticscholar   +1 more source

3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. [PDF]

PLoS ONE, 2010
Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET).
Andrew H Beck, Ziming Weng, Daniela M Witten, Shirley Zhu, Joseph W Foley, Phil Lacroute, Cheryl L Smith, Robert Tibshirani, Matt van de Rijn, Arend Sidow, Robert B West   +10 more
doaj   +1 more source

Gene expression profile of pulpitis [PDF]

Genes & Immunity, 2016
The cost, prevalence and pain associated with endodontic disease necessitate an understanding of the fundamental molecular aspects of its pathogenesis. This study was aimed to identify the genetic contributors to pulpal pain and inflammation. Inflamed pulps were collected from patients diagnosed with irreversible pulpitis (n=20).
Johnah C. Galicia, Asma A. Khan, Joel S. Parker, Brett R. Henson   +3 more
openaire   +3 more sources

Pathway-targeting gene matrix for Drosophila gene set enrichment analysis

PLoS ONE, 2021
Gene Set Enrichment Analysis (GSEA) is a powerful algorithm to determine biased pathways between groups based on expression profiling. However, for fruit fly, a popular animal model, gene matrixes for GSEA are unavailable. This study provides the pathway-
Jack Cheng, Lee-Fen Hsu, Ying-Hsu Juan, Hsin-Ping Liu, Wei-Yong Lin   +4 more
doaj   +2 more sources

Gene expression profiling of skeletal muscles [PDF]

Genes, 2021
AbstractSoleus and tibialis anterior are two well-characterized skeletal muscles commonly utilized in skeletal muscle-related studies. Next-generation sequencing provides an opportunity for an in-depth biocomputational analysis to identify the gene expression patterns between soleus and tibialis anterior and analyze those genes’ functions based on past
Sarah I. Alto, Chih-Ning Chang, Kevin Brown, Chrissa Kioussi, Theresa M. Filtz   +4 more
openaire   +4 more sources

Gene Expression Profiling

Encyclopedia of Molecular Pharmacology, 2021
Property of EmblemHealth. All rights reserved. The treating physician or primary care provider must submit to EmblemHealth the clinical evidence that the patient meets the criteria for the treatment or surgical procedure.
B. F. Hasson, Brandon J. Fisher, L. Daugherty, Filip T. Troicki, J. Poli, Claudia Rübe, S. Varnum, M. Sowa, W. Morgan, Ning J. Yue, Johannes Classen, Carlos A. Perez, W. Thorstad, J. Chalal, Carsten Nieder   +14 more
semanticscholar   +1 more source

Global assessment of organ specific basal gene expression over a diurnal cycle with analyses of gene copies exhibiting cyclic expression patterns

BMC Genomics, 2020
Background Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution.
Yuan Lu, Mikki Boswell, William Boswell, Raquel Ybanez Salinas, Markita Savage, Jose Reyes, Sean Walter, Rebecca Marks, Trevor Gonzalez, Geraldo Medrano, Wesley C. Warren, Manfred Schartl, Ronald B. Walter   +12 more
doaj   +1 more source

Gene Expression Profiling

European Journal of Cancer Supplements, 2008
Gene expression profiling measures the relative abundance of a large number of individual mRNA species within the context of a total mRNA population that has been isolated and purified from a target biological sample. The technology for achieving this evolved from low-Throughput membrane-based probeto- target hybridization assays (northern and Southern
Druka, Arnis, Waugh, Robbie, Hedley, Pete   +2 more
openaire   +5 more sources

Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer [PDF]

Einstein (São Paulo), 2011
Objective: To compare the prognosis estimated by standardprognostic criteria versus the prognosis estimated by the OncotypeDX. Methods: A retrospective study was performed on 22 patientswith positive estrogen receptor, early-stage breast cancer whohad an
Marcelo Roberto Pereira Freitas, Sergio Daniel Simon   +1 more
doaj   +4 more sources

Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading [PDF]

Endocrinology and Metabolism, 2020
Background We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical unloading on bone loss ...
A Ram Hong, Kwangsoo Kim, Ji Yeon Lee, Jae-Yeon Yang, Jung Hee Kim, Chan Soo Shin, Sang Wan Kim   +6 more
doaj   +1 more source