Results 221 to 230 of about 809,277 (348)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignancies. [PDF]

PLoS One
Yu S, Qian L, Tong T, Ma X.
europepmc   +1 more source

Expression Profiling Identifies the CRH/CRH-R1 System as a Modulator of Neurovascular Gene Activity [PDF]

, 2007
Jan M. Deussing, Claudia Kühne, Benno Pütz, Markus Panhuysen, Johannes Breu, Mary P. Stenzel‐Poore, Herta Flor, Wolfgang Wurst   +7 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and <i>in silico</i> gene expression profiling. [PDF]

Front Immunol
Di Salvatore V, Cernuto F, Russo G, Pappalardo F.   +3 more
europepmc   +1 more source

PF530 CORRELATION OF CD10 EXPRESSION DETERMINED BY FLOW CYTOMETRIC IMMUNOPHENOTYPING AND CELL-OF-ORIGIN DETERMINATION BY GENE EXPRESSION PROFILING IN DIFFUSE LARGE B-CELL LYMPHOMA

, 2019
Ryan S. Robetorye, Colleen Ramsower, Tameson Yip, Lisa M. Rimsza   +3 more
openalex   +1 more source

Aspen phenylpropanoid genes’ expression levels correlate with genets’ tannin richness and vary both in responses to soil nitrogen and associations with phenolic profiles [PDF]

, 2016
Vicki Huizu Guo Decker, Franziska Bandau, Michael J. Gundale, Christopher T. Cole, Benedicte Riber Albrectsen   +4 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Gene Expression Profiles

Report related to the Massive amount gene expression profiles related to tested food along the food chain - In particular spoilage and safety aspects will be ...
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source