Results 251 to 260 of about 2,789,846 (387)

Gene expression profiling in human neurodegenerative disease

Nature Reviews Neurology, 2012
Johnathan Cooper-Knock, J. Kirby, L. Ferraiuolo, P. Heath, M. Rattray, P. Shaw   +5 more
semanticscholar   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

Molecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová, Hana Svozilová, Marcela Krzyžánková, Radim Sonnek, Anastasiya Volakhava, Anastasia Smirnova, Tatiana Grigoreva, Zuzana Jašková, Hana Synáčková, Dennis Wahl, Michaela Bilčíková, Libor Červinek, Šárka Pospíšilová, Ilgar Mamedov, Karla Plevová   +14 more
wiley   +1 more source

Gene expression profiling of human umbilical vein endothelial cells overexpressing CELF2 as diagnostic targets in diabetes-induced erectile dysfunction. [PDF]

Front Mol Biosci
Nuerdebieke D, Yao L, Guo L, Li J, Jia H, Nan Y.   +5 more
europepmc   +1 more source

Protective effect of incadronate on OVX-induced osteopenia in mice and effect-related changes in gene-expression profile of bone cells: a preliminary study

, 2000
Nobuo Izumo, Tsuneo Fujita, Ryo Fukuyama, Toshikazu Hattori, Torn Meguro, Hiromichi Nakamuta, Masao Koida   +6 more
openalex   +1 more source

Profiling Changes in Gene Expression during Differentiation and Maturation of Monocyte-derived Dendritic Cells Using Both Oligonucleotide Microarrays and Proteomics [PDF]

, 2001
François Le Naour, Lyndon Hohenkirk, Annabelle Grolleau, David E. Misek, Pascal Lescure, James D. Geiger, Samir Hanash, Laura Beretta   +7 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A comparative analysis of gene expression profiling by statistical and machine learning approaches. [PDF]

Bioinform Adv
Bontonou M, Haget A, Boulougouri M, Audit B, Borgnat P, Arbona JM.   +5 more
europepmc   +1 more source

Application of Principal Component Analysis to Gene Expression Profiling by cDNA Microarray in Rice Seminal Root under Low pH Condition

, 2000
Eiji Domon, Naoki Kishimoto, Shoshi Kikuchi, Junji Yazaki, Takuji Sasaki, Katsumi Sakata, Kimiko Yamamoto, Akira Saito   +7 more
openalex   +2 more sources

Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE) [PDF]

, 2001
Dror Sharon, Seth Blackshaw, Constance L. Cepko, Thaddeus P. Dryja   +3 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source