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Gene expression profiling of lymphomas
Current Oncology Reports, 2001The functional phenotype of a cell results from the simultaneous action of many thousands of genes, which until recently could not be assessed using standard molecular biological techniques. Indeed, molecular genetics and cellular biology inadequately explain the molecular physiology of normal and diseased cells and provide a fragmented view of the ...
U, Hegde, W H, Wilson
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Tumor-specific gene expression patterns with gene expression profiles
Science in China Series C, 2006Gene expression profiles of 14 common tumors and their counterpart normal tissues were analyzed with machine learning methods to address the problem of selection of tumor-specific genes and analysis of their differential expressions in tumor tissues. First, a variation of the Relief algorithm, "RFE_Relief algorithm" was proposed to learn the relations ...
Xiaogang, Ruan +4 more
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Tissue Classification with Gene Expression Profiles
Journal of Computational Biology, 2000Constantly improving gene expression profiling technologies are expected to provide understanding and insight into cancer-related cellular processes. Gene expression data is also expected to significantly aid in the development of efficient cancer diagnosis and classification platforms.
A, Ben-Dor +5 more
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Gene Expression Profiling in Asthma
2013Transcriptomics (gene expression profiling) refers to the quantitative and qualitative characterization of the collection of ribose nucleic acid (RNA) elements expressed in a biological system and represents one of the first truly genome-wide hypothesis-free investigative approaches in molecular biology.
Joanne, Sordillo, Benjamin A, Raby
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Expression Profiling of Organellar Genes
2012Due to their endosymbiotic origin, expression of plastid and mitochondrial genes retains several features of prokaryotes. Nevertheless, plant organelles acquired novel specific traits during evolution. Furthermore, due to the migration of many genes to the nucleus of the host cell, complex anterograde and retrograde signalling pathways evolved to ...
Cardi T, Giegé P, Kahlau S, Scotti N
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Gene expression profiling and multiple myeloma
Best Practice & Research Clinical Haematology, 2005Gene expression profiling is a powerful tool through which the biology of multiple myeloma can be dissected. We will describe in this chapter how early studies using this technology have provided meaningful insights into myeloma biology, have led to the identification of new therapeutic targets, and have identified powerful prognostic and ...
John, Shaughnessy +3 more
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2010
Gene expression (GE) analyses by use of microarrays (MAs) have become an important part of biomedical and clinical research and the resulting data may provide important information regarding pathogenesis and be extrapolated for use in diagnosing/prognosticating lymphomas and leukemias.
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Gene expression (GE) analyses by use of microarrays (MAs) have become an important part of biomedical and clinical research and the resulting data may provide important information regarding pathogenesis and be extrapolated for use in diagnosing/prognosticating lymphomas and leukemias.
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Methods to Profile Gene Expression
Trends in Cardiovascular Medicine, 2001Molecular biology has been influenced tremendously by recent technological advancements in miniaturization and automation. One consequence has been the development of robust and sensitive methods to analyze gene expression. The ability to evaluate systematically the expression of every mammalian gene is now technically feasible.
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Gene Expression Profiling of Rat Pheochromocytoma
Annals of the New York Academy of Sciences, 2006Abstract: Sporadic and syndrome‐associated human pheochromocytomas exhibit a spectrum of common and distinctive phenotypic markers. Animal models may contribute to understanding of common denominators leading to development and progression of pheochromocytoma, and to mechanisms that underlie distinctive phenotypes.
Abdel G, Elkahloun +4 more
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Gene-expression profiles in murine melioidosis
Microbes and Infection, 2008Melioidosis, caused by the bacterium Burkholderia pseudomallei, is a septicemic illness, often associated with pneumonia and bacterial dissemination to distant sites. Recently we reported the inflammatory mRNA profile in blood leukocytes during human melioidosis.
Wiersinga, W. Joost +2 more
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