Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin. [PDF]
Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture.
Ahn, Richard S+9 more
core +1 more source
AIM Can gene expression profiling be used to identify patients with T1-T2 melanoma at low risk for sentinel lymph node (SLN) positivity? PATIENTS & METHODS Bioinformatics modeling determined a population in which a 31-gene expression profile test ...
J. Vetto+14 more
semanticscholar +1 more source
Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]
It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J+7 more
core +4 more sources
Significance The spatial organization of RNAs within cells and spatial patterning of cells within tissues play crucial roles in many biological processes.
C. Xia+4 more
semanticscholar +1 more source
Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]
Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran+5 more
core +2 more sources
Joint profiling of chromatin accessibility and gene expression in thousands of single cells
Single-cell chromatin and RNA analysis Single-cell analyses have begun to provide insight into the differences among and within the individual cells that make up a tissue or organism.
Junyue Cao+13 more
semanticscholar +1 more source
Gene expression profiling of the inner ear [PDF]
AbstractThe identification of transcriptional differences has served as an important starting point in understanding the molecular mechanisms behind biological processes and systems. The developmental biology of the inner ear, the biology of hearing and of course the pathology of deafness are all processes that warrant a molecular description if we are
Schimmang, Thomas, Maconochie, Mark
openaire +3 more sources
Transcriptome analysis of bladder biopsy from interstitial cystitis/bladder pain syndrome patients
Interstitial cystitis and bladder pain syndrome (IC/BPS) are terms used to describe a heterogeneous chronic pelvic and bladder pain disorder. Despite its significant prevalence, the disease etiology is not well understood and providing diagnosis and ...
Stephen J. Walker+6 more
doaj +1 more source
Gene expression profiling to predict responsiveness to immunotherapy
Recent clinical successes with immunotherapy have resulted in expanding indications for cancer therapy. To enhance antitumor immune responses, and to better choose specific strategies matched to patient and tumor characteristics, genomic-driven precision
N. Jamieson, A. Maker
semanticscholar +1 more source
Gene expression profile of sprinter’s muscle [PDF]
We have characterized the global gene expression profile in left vastus lateralis muscles of sprinters and sedentary men. The gene expression profile was analyzed by using serial analysis of gene expression (SAGE) method. The abundantly expressed transcripts in the sprinter's muscle were mainly involved in contraction and energy metabolism, whereas six
Munehiro Shindo+4 more
openaire +3 more sources