Results 51 to 60 of about 918,366 (270)

Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling. [PDF]

, 2010
Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We used integrative molecular profiling to discover and characterize molecular subtypes of LMS.
Beck, A, Edris, B, Espinosa, I, Fletcher, C, Gleason, B, Hastie, T, Jablons, David, Lee, C-H, Li, R, Marinelli, R, Montgomery, K, Rubin, B, Tibshirani, R, van de Rijn, M, West, R, Witten, D, Zhu, S   +16 more
core  

Genomic profiling of CHEK2*1100delC-mutated breast carcinomas [PDF]

, 2015
Background: CHEK2*1100delC is a moderate-risk breast cancer susceptibility allele with a high prevalence in the Netherlands. We performed copy number and gene expression profiling to investigate whether CHEK2*1100delC breast cancers harbor characteristic
A Bergamaschi, A Hirao, A Stolz, AC Antoniou, B Evers, C Cybulski, EH Beers van, EN Suspitsin, G Jonsson, GH Bock de, H Meijers-Heijboer, H Takai, Hanne Meijers-Heijboer, Irsan E. Kooi, J Bartek, J Staaf, JH Nagel, John W. M. Martens, LF Wessels, M Smid, M Tirkkonen, MA Adank, Maarten P. G. Massink, N Waddell, O Anczukow, P Bouwman, PJ Diest van, Quinten Waisfisz, RA Oldenburg, RE Ellsworth, SD Merajver, T Sorlie, TA Muranen, V Staalesen, YC Lin   +34 more
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Potential Roles of miRNA-1245a Regulatory Networks in Sarcopenia

International Journal of General Medicine, 2021
Li An,1 Yao Wang2 1Department of Geriatrics, Zhongda Hospital Southeast University,, Nanjing City, People’s Republic of China; 2Department of Endocrine, Zhongda Hospital Southeast University, Nanjing City, People’s Republic of ChinaCorrespondence: Yao ...
An L, Wang Y
doaj  

Microarray gene expression profiling of neural tissues in bovine spastic paresis [PDF]

, 2013
: Background: Bovine Spastic Paresis (BSP) is a neuromuscular disorder which affects both male and female cattle. BSP is characterized by spastic contraction and overextension of the gastrocnemious muscle of one or both limbs and is associated with a ...
Bicorgna, S., Bongiorni, S., Bueno, S., Chillemi, Giovanni, Gentile, A., Gruber Ce, Gruber Cem, Pariset, L., Prosperini, G., Valentini, Alessio   +9 more
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Gene expression profiling of solitary fibrous tumors. [PDF]

PLoS ONE, 2013
Solitary fibrous tumors (SFTs) are rare spindle-cell tumors. Their cell-of-origin and molecular basis are poorly known. They raise several clinical problems.
François Bertucci, Corinne Bouvier-Labit, Pascal Finetti, Philippe Metellus, José Adelaide, Karima Mokhtari, Dominique Figarella-Branger, Anne-Valérie Decouvelaere, Catherine Miquel, Jean-Michel Coindre, Daniel Birnbaum   +10 more
doaj   +1 more source

Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men [PDF]

Moderate alcohol consumption has various effects on immune and inflammatory processes, which could accumulatively modulate chronic disease risk. So far, no comprehensive, integrative profiling has been performed to investigate the effects of longer-term ...
Erk, M.J., van, Hendriks, H.F.J., Joosten, M.M., Pellis, E.P.M., Witkamp, R.F.   +4 more
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Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. [PDF]

, 2016
BackgroundOur previous studies showed that the non-psychoactive cannabinoid, cannabidiol (CBD), ameliorates the clinical symptoms in mouse myelin oligodendrocyte glycoprotein (MOG)35-55-induced experimental autoimmune encephalomyelitis model of multiple ...
Coppola, Giovanni, Gao, Fuying, Juknat, Ana, Kaushansky, Nathali, Kozela, Ewa, Vogel, Zvi   +5 more
core   +2 more sources

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

eLife, 2016
Mammalian lifespan differs by >100 fold, but the mechanisms associated with such longevity differences are not understood. Here, we conducted a study on primary skin fibroblasts isolated from 16 species of mammals and maintained under identical cell ...
Siming Ma, Akhil Upneja, Andrzej Galecki, Yi-Miau Tsai, Charles F Burant, Sasha Raskind, Quanwei Zhang, Zhengdong D Zhang, Andrei Seluanov, Vera Gorbunova, Clary B Clish, Richard A Miller, Vadim N Gladyshev   +12 more
doaj   +1 more source

A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics [PDF]

, 2019
Cellular, organ, and whole animal physiology show temporal variation predominantly featuring 24-h (circadian) periodicity. Time-course mRNA gene expression profiling in mouse liver showed two subsets of genes oscillating at the second (12-h) and third (8-
Biagini, Tommaso, Capocefalo, Daniele, Carbone, Annalucia, Castellana, Stefano, Genov, Nikolai, Mazza, Tommaso, Mazzoccoli, Gianluigi, Relógio, Angela, Rosati, Jessica, Scholkmann, Felix, Truglio, Mauro, Turco, Elisa Maria   +11 more
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Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. [PDF]

, 2016
We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting.
Avetisyan, Rozeta, Gong, Ke Wei, Lusis, Aldons J, Rau, Christoph, Ren, Shuxun, Romay, Milagros C, Stolin, Gabriel, Wang, Jessica Jen-Chu, Wang, Yibin   +8 more
core   +3 more sources