Imaging cell lineage with a synthetic digital recording system [PDF]
, 2020 Cell lineage plays a pivotal role in cell fate determination. Chow et al. demonstrate the use of an integrase-based synthetic barcode system called intMEMOIR, which uses the serine integrase Bxb1 to perform irreversible nucleotide edits.
Budde, Mark W. +11 more
core +1 more source
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements [PDF]
PNAS vol 100, p 7853 (2003), 2005 The ALL-1 gene is directly involved in 5-10% of ALLs and AMLs by fusion to other genes or through internal rearrangements. DNA microarrays were utilized to determine expression profiles of ALLs and AMLs with ALL-1 rearrangements. These profiles distinguish those tumors from other ALLs and AMLs.
arxiv +1 more source
Gene expression profiles of apoptotic neurons
Genomics, 2004 The multigenic program underlying neuronal apoptosis is mostly unknown. To study the program, we used genome-scale screening by oligonucleotide microarrays during serum and potassium deprivation-induced apoptosis of cerebellar granule neurons.
CAVALLARO S +10 more
openaire +6 more sources
BMC Genomics, 2009 Background Serial analysis of gene expression (LongSAGE) was applied for gene expression profiling in seeds of oilseed rape (Brassica napus ssp. napus).
Friedt Wolfgang +3 more
doaj +1 more source
Classification of chemical compounds based on the correlation between \textit{in vitro} gene expression profiles [PDF]
Bulletin of Informatics and Cybernetics, 53(4) (2021), 1-14, 2021 Toxicity evaluation of chemical compounds has traditionally relied on animal experiments;however, the demand for non-animal-based prediction methods for toxicology of compounds is increasing worldwide. Our aim was to provide a classification method for compounds based on \textit{in vitro} gene expression profiles.
arxiv
Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]
, 2012 It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J +7 more
core +4 more sources
Development and validation of a skin fibroblast biomarker profile for schizophrenic patients
AIMS Bioengineering, 2016 Gene expression profiles of non-neural tissues through microarray technology could be used in schizophrenia studies, adding more information to the results from similar studies on postmortem brain tissue.
Marianthi Logotheti +4 more
doaj +1 more source
Marker Genes for Anatomical Regions in the Brain: Insights from the Allen Gene Expression Atlas [PDF]
arXiv, 2011 Quantitative criteria are proposed to identify genes (and sets of genes) whose expression marks a specific brain region (or a set of brain regions). Gene-expression energies, obtained for thousands of mouse genes by numerization of in-situ hybridization images in the Allen Gene Expression Atlas, are used to test these methods in the mouse brain ...
arxiv
Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]
, 2019 Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate coordinated gene expression.
arxiv +1 more source
Identification of transcriptional regulatory networks specific to pilocytic astrocytoma. [PDF]
, 2011 BackgroundPilocytic Astrocytomas (PAs) are common low-grade central nervous system malignancies for which few recurrent and specific genetic alterations have been identified.
Deshmukh, Hrishikesh +8 more
core +3 more sources