Results 31 to 40 of about 3,713,851 (363)
Cell Reports, 2016 Epithelial-to-mesenchymal transition (EMT) confers several traits to cancer cells that are required for malignant progression. Here, we report that miR-27b-3p-mediated silencing of the single-strand RNA binding protein KHSRP is required for transforming ...
Margherita Puppo +8 more
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Gene expression regulation and cancer
Clinical and Translational Oncology, 2006 Gene expression is mostly controlled at the level of the transcription initiation. The transcription control regions of protein-encoding genes include: the core promoter, where RNA polymerase II binds, the proximal and distal promoter, responsible for gene expression regulation, and the enhancers and silencers.
Delgado, M. Dolores, León, Javier
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Single-Cell and Single-Molecule Analysis of Gene Expression Regulation.
Annual Review of Genetics, 2016 Recent advancements in single-cell and single-molecule imaging technologies have resolved biological processes in time and space that are fundamental to understanding the regulation of gene expression.
Maria Vera +4 more
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Scientific Reports, 2017 Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C.
Sarah-Lena Offenburger +4 more
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Open Biology, 2021 Treslin/Ticrr is required for the initiation of DNA replication and binds to MTBP (Mdm2 Binding Protein). Here, we show that in Xenopus egg extract, MTBP forms an elongated tetramer with Treslin containing two molecules of each protein.
Ilaria Volpi +3 more
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BMC Genomics, 2015 DNA methylation plays an important role in regulating gene expression during many biological processes. However, the mechanism of DNA-methylation-dependent gene regulation is not fully understood.
Jun Wan +6 more
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A role for p53 in telomere protection
Molecular & Cellular Oncology, 2017 Telomeres cap the ends of chromosomes and are crucial for genome stability. The p53 protein (TP53) is a vital tumor suppressor, activating the transcription of numerous genes in response to cell stress.
Stephen Tutton, Paul M. Lieberman
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The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element
Genome Biology, 2017 Background It is now obvious that the majority of cellular transcripts do not code for proteins, and a significant subset of them are long non-coding RNAs (lncRNAs).
Oskar Marín-Béjar +12 more
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Regulated gene expression in methanogens [PDF]
FEMS Microbiology Reviews, 1994 Methanogens form a very large and diverse group of microorganisms within the domain of the Archaea. Energy for their growth is obtained by the reduction of a variety of substrates into methane. Several genes, coding for enzymes involved in methanogenesis or in the central metabolism have been cloned and studied.
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Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology and Disease
Non-Coding RNA, 2019 The identification of RNAs that are not translated into proteins was an important breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene expression. These non-coding RNAs can be divided into two main classes according
J. C. R. Fernandes +4 more
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