Population and pangenome analyses uncover the evolutionary dynamics of the peroxidase gene family in barley. [PDF]
Ke Q +8 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Telegram from Gene Autry to Amon G. Carter, Jr. and Family
Telegram from Gene Autry to Amon G. Carter, Jr. and Family to Minnie Meacham Carter upon the death of Amon Giles Carter. The telegram expresses condolences about his death.https://mavmatrix.uta.edu/specialcollections_meachamcarterpapers/1384/thumbnail ...
Autry, Gene
core
The role of the <i>CDCA</i> gene family in tumor stemness maintenance and drug sensitivity. [PDF]
Xiang L +4 more
europepmc +1 more source
SUC Genes of Yeast: A Dispersed Gene Family
M, Carlson, B C, Osmond, D, Botstein
openaire +2 more sources
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Genome-Wide Characterization of the WOX Gene Family in <i>Polygonatum cyrtonema</i> and Its Applications for Regeneration. [PDF]
Shi Y, Huang B, Li C, Si J, Chen D.
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Clinical and Genetic Landscape of Glioblastoma, IDH-Wildtype With FGFR Gene Family Alterations. [PDF]
Kegoya Y +9 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source

