Results 51 to 60 of about 12,462,452 (401)
Update on the aldehyde dehydrogenase gene (
Human Genomics, 2011 Members of the aldehyde dehydrogenase gene (ALDH) superfamily play an important role in the enzymic detoxification of endogenous and exogenous aldehydes and in the formation of molecules that are important in cellular processes, like retinoic acid ...
Jackson Brian +6 more
doaj +1 more source
CRISPR-Cas9-Mediated Single-Gene and Gene Family Disruption in Trypanosoma cruzi
mBio, 2014 Trypanosoma cruzi is a protozoan parasite of humans and animals, affecting 10 to 20 million people and innumerable animals, primarily in the Americas. Despite being the largest cause of infection-induced heart disease worldwide, even among the neglected ...
D. Peng +4 more
semanticscholar +1 more source
Evolutionary divergence and functions of the human interleukin (IL) gene family
Human Genomics, 2010 Cytokines play a very important role in nearly all aspects of inflammation and immunity. The term 'interleukin' (IL) has been used to describe a group of cytokines with complex immunomodulatory functions -- including cell proliferation, maturation ...
Brocker Chad +4 more
doaj +1 more source
Nucleic Acids Res., 2020 PANTHER (Protein Analysis Through Evolutionary Relationships, http://www.pantherdb.org) is a resource for the evolutionary and functional classification of protein-coding genes from all domains of life.
H. Mi +6 more
semanticscholar +1 more source
Pigmentation Genes: the Tyrosinase Gene Family and the pmel 17 Gene Family.
Journal of Investigative Dermatology, 1993 We propose that at least two families of genes regulate the melanin biosynthesis. The first is the tyrosinase gene family, which is comprised of tyrosinase (c locus), gp75 (b locus) and DOPAchrome tautomerase (slt locus). The second is the pmel 17 gene family, which is composed of pmel 17 (putative si locus) and chicken melanosomal matrix protein (MMP)
openaire +3 more sources
Coevolution of gene families in prokaryotes [PDF]
Genome Research, 2008 We study gene family coevolution on a tree of life based on a large-scale ancestral gene content reconstruction, which includes gene duplication and deletion events. The insights obtained from this study are threefold: (1) Global properties, such as the distribution of coevolution partners and the formation of disconnected clusters of coevolving ...
Paulien Hogeweg +2 more
openaire +4 more sources
A probabilistic model for gene content evolution with duplication, loss, and horizontal transfer
, 2005 We introduce a Markov model for the evolution of a gene family along a phylogeny. The model includes parameters for the rates of horizontal gene transfer, gene duplication, and gene loss, in addition to branch lengths in the phylogeny. The likelihood for
A.B. Simonson +43 more
core +2 more sources
Frontiers in Plant Science, 2023 3-Ketoacyl-CoA synthase (KCS) is the key rate-limiting enzyme for the synthesis of very long-chain fatty acids (VLCFAs) in plants, which determines the carbon chain length of VLCFAs.
Lingwei Yang +19 more
doaj +1 more source
GreenPhylDB: A Gene Family Database for plant functional Genomics [PDF]
, 2009 With the increasing number of genomes being sequenced, a major objective is to transfer accurate annotation from characterised proteins to uncharacterised sequences.
Christophe Pé +3 more
core +2 more sources
Characterization and expression analysis of growth regulating factor (GRF) family genes in cucumber [PDF]
Archives of Biological Sciences, 2018 The growth regulating factor (GRF) family is a conserved class of transcription factors involved in various biological processes in plants. However, there have been only a few studies of the GRF family genes in cucumber, Cucumis sativus (Cs).
Zhou Yong +4 more
doaj +1 more source