Results 51 to 60 of about 7,504,063 (305)

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Cloning of a Carcinoembryonic Antigen Gene Family Member Expressed in Leukocytes of Chronic Myeloid Leukemia Patients and Bone Marrow [PDF]

, 1990
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin superfamily and can be subdivided into the CEA and pregnancy-specific glycoprotein subgroups.
Kolbinger, Frank, Zimmermann, Wolfgang, Grunert, Fritz, Buchegger, Franz, Berling, Barbara, Brombacher, Frank, Thompson, John A., Kleist, Sabine von   +7 more
core   +1 more source

Genomic Fishing and Data Processing for Molecular Evolution Research

Methods and Protocols, 2022
Molecular evolution analyses, such as detection of adaptive/purifying selection or ancestral protein reconstruction, typically require three inputs for a target gene (or gene family) in a particular group of organisms: sequence alignment, model of ...
Héctor Lorente-Martínez, Ainhoa Agorreta, Diego San Mauro   +2 more
doaj   +1 more source

The grapevine Pectin Methylesterases gene family and its involvement in Botrytis bunch rot control [PDF]

, 2022
Plant Pectin Methylesterases (PMEs) represent a group of tissue-specific and developmentally regulated proteins. The gene family is involved in the plant cell wall (CW) remodelling process, by the control of the degree of cell wall pectin ...
Moretto, Marco, Lagreze, Jorge, Matus, Tomás, Malacarne, Giulia, Moser, Claudio   +4 more
core  

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Genome-Wide Identification of Chalcone Reductase Gene Family in Soybean: Insight into Root-Specific GmCHRs and Phytophthora sojae Resistance

Frontiers in Plant Science, 2017
Soybean (Glycine max [L.] Merr) is one of the main grain legumes worldwide. Soybean farmers lose billions of dollars’ worth of yield annually due to root and stem rot disease caused by the oomycete Phytophthora sojae.
Caroline J. Sepiol, Caroline J. Sepiol, Jaeju Yu, Sangeeta Dhaubhadel, Sangeeta Dhaubhadel   +4 more
doaj   +1 more source

Genome-Wide Classification and Evolutionary Analysis Reveal Diverged Patterns of Chalcone Isomerase in Plants

Biomolecules, 2022
Flavonoids as a class of important secondary metabolites are widely present in land plants, and chalcone isomerase (CHI) is the key rate-limiting enzyme that participates in catalyzing the stereospecific isomerization of chalcones to yield their ...
Jianyong Wang, Yifei Jiang, Tong Sun, Chenhao Zhang, Xuhui Liu, Yangsheng Li   +5 more
doaj   +1 more source

Molecular evolution and functional characterization of chitinase gene family in Populus trichocarpa

, 2022
Chitinases, the chitin-degrading enzymes, have been shown to play important role in defense against the chitincontaining fungal pathogens. In this study, we identified 48 chitinase-coding genes from the woody model plant Populus trichocarpa.
Han, Xue-Min, Wang, Wei, Zhang, Yuan-Jie, Lin, Xiao-Yang, Ren, Lin-Ling, Yang, Zhi-Ling   +5 more
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Genome-wide analysis of the Solanum tuberosum (potato) trehalose-6-phosphate synthase (TPS) gene family: evolution and differential expression during development and stress

BMC Genomics, 2017
Background Trehalose-6-phosphate synthase (TPS) serves important functions in plant desiccation tolerance and response to environmental stimuli. At present, a comprehensive analysis, i.e.
Yingchun Xu, Yanjie Wang, Neil Mattson, Liu Yang, Qijiang Jin   +4 more
doaj   +1 more source