Results 1 to 10 of about 1,078,640 (312)

Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

Journal for ImmunoTherapy of Cancer, 2021
Background Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the ...
Malcolm K Brenner, Valentina Hoyos, Ignazio Caruana, Gerrit Weber, Claudia Manuela Arnone, Vinicia Assunta Polito, Angela Mastronuzzi, Andrea Carai, Francesca Camassei Diomedi, Laura Antonucci, Maria Vinci, Francesco Ferrari, Elisa Salviato, Marco Scarsella, Cristiano De Stefanis, Lucia Lisa Petrilli   +15 more
doaj   +1 more source

Gene Flow Disruption and Population Declines in a Soil Arthropod in Fragmented Habitats. [PDF]

Mol Ecol
Ho TAT, Pedersen JB, Aagaard A, Schou MF, Bechsgaard J, Corcoran D, Jørgensen TH, Normand S, Bilde T.   +8 more
europepmc   +2 more sources

Comparing Genetic and Field-Based Estimates of Population Connectivity in Marbled Salamanders, Ambystoma opacum

Diversity, 2022
Estimating connectivity is key for maintaining population viability for pond-breeding amphibians, especially in areas where habitat alterations occur. Here, we used genetic data (microsatellites) to estimate connectivity of marbled salamanders, Ambystoma
Karine E. Posbic-Leydet, Kelsey L. Glennon, Jolene T. Fisher, Don R. Church, Sheri A. Church   +4 more
doaj   +1 more source

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

Frontiers in Physiology, 2020
Chronic pancreatitis, a known risk factor for the development of pancreatic ductal adenocarcinoma (PDA), is a serious, widespread medical condition characterized by inflammation, fibrosis, and acinar to ductal metaplasia (ADM).
Kathleen E. DelGiorno, Razia F. Naeem, Linjing Fang, Chi-Yeh Chung, Cynthia Ramos, Natalie Luhtala, Carolyn O’Connor, Tony Hunter, Uri Manor, Geoffrey M. Wahl   +9 more
doaj   +1 more source

Genome‐scale phylogeography resolves the native population structure of the Asian longhorned beetle, Anoplophora glabripennis (Motschulsky)

Evolutionary Applications, 2022
Human‐assisted movement has allowed the Asian longhorned beetle (ALB, Anoplophora glabripennis (Motschulsky)) to spread beyond its native range and become a globally regulated invasive pest.
Mingming Cui, Yunke Wu, Marion Javal, Isabelle Giguère, Géraldine Roux, Jose A. Andres, Melody Keena, Juan Shi, Baode Wang, Evan Braswell, Scott E. Pfister, Richard Hamelin, Amanda Roe, Ilga Porth   +13 more
doaj   +1 more source

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

eLife, 2017
The temporal regulation of protein abundance and post-translational modifications is a key feature of cell division. Recently, we analysed gene expression and protein abundance changes during interphase under minimally perturbed conditions (Ly et al ...
Tony Ly, Arlene Whigham, Rosemary Clarke, Alejandro J Brenes-Murillo, Brett Estes, Diana Madhessian, Emma Lundberg, Patricia Wadsworth, Angus I Lamond   +8 more
doaj   +1 more source

Assessment of genetic relationships among native and introduced Himalayan balsam (Impatiens glandulifera) plants based on genome profiling

Ecology and Evolution, 2021
We conducted genomic characterization based on SNP and SilicoDArT markers on the invasive Himalayan balsam (Impatiens glandulifera) plants originating from native and non‐native regions of their distribution.
Helena Korpelainen, Sakina Elshibli
doaj   +1 more source

When gene flow really matters: gene flow in applied evolutionary biology [PDF]

Evolutionary Applications, 2016
In the last half century, gene flow has moved from relative obscurity to a well‐recognized component of evolution. Gene flow, the successful transfer of alleles from one population to another, is now known to vary considerably among species, populations, and individuals as well as over time. It frequently occurs at rates sufficient to play an important
Ellstrand, Norman C, Rieseberg, Loren H
openaire   +4 more sources

Courtship behavior, nesting microhabitat, and assortative mating in sympatric stickleback species pairs

Ecology and Evolution, 2021
The maintenance of reproductive isolation in the face of gene flow is a particularly contentious topic, but differences in reproductive behavior may provide the key to explaining this phenomenon.
Laura L. Dean, Hannah R. Dunstan, Amelia Reddish, Andrew D. C. MacColl   +3 more
doaj   +1 more source

Wild and cultivated olive tree genetic diversity in Greece: a diverse resource in danger of erosion

Frontiers in Genetics, 2023
The genetic relationships between Greek wild olive tree populations and cultivars were investigated. A total of 219 wild genotypes and 67 cultivar genotypes were analyzed by employing 10 SSR markers.
Nikolaos Tourvas, Ioannis Ganopoulos, Georgios Koubouris, George Kostelenos, Ioannis Manthos, Christos Bazakos, Christos Bazakos, Vasileios Stournaras, Athanassios Molassiotis, Filippos Aravanopoulos   +9 more
doaj   +1 more source