Results 41 to 50 of about 1,168,362 (261)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

GENE FLOW AND SELECTION IN A CLINE [PDF]

Genetics, 1973
ABSTRACT A model of the effect of gene flow and natural selection in a continuously distributed, infinite population is developed. Different patterns of spatial variation in selective pressures are considered, including a step change in the environment, a "pocket" in the environment and a periodically varying environment.
openaire   +2 more sources

Inteins as indicators of gene flow in the halobacteria [PDF]

Frontiers in Microbiology, 2014
This research uses inteins, a type of mobile genetic element, to infer patterns of gene transfer within the Halobacteria. We surveyed 118 genomes representing 26 genera of Halobacteria for intein sequences. We then used the presence-absence profile, sequence similarity and phylogenies from the inteins recovered to explore how intein distribution can ...
Soucy, Shannon M., Fullmer, Matthew S., Papke, R. Thane, Gogarten, Johann Peter   +3 more
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Genetic divergence and one‐way gene flow influence contemporary evolution and ecology of a partially migratory fish

Evolutionary Applications
Recent work has revealed the importance of contemporary evolution in shaping ecological outcomes. In particular, rapid evolutionary divergence between populations has been shown to impact the ecology of populations, communities, and ecosystems.
Katie M. Kobayashi, Rosealea M. Bond, Kerry Reid, J. Carlos Garza, Joseph D. Kiernan, Eric P. Palkovacs   +5 more
doaj   +1 more source

A theory of measuring natural selection and genetic monitoring

Communicative & Integrative Biology
Two methods have been compared for determining the value of natural selection in the natural populations. The first method, based on the FST-statistics, employs the dependence of genetic diversity of a species on the value of gene flow between ...
A. I. Yuriev
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Genetic consequences of improved river connectivity in brown trout (Salmo trutta L.)

Evolutionary Applications
Fragmentation of watercourses poses a significant threat to biodiversity, particularly for migratory fish species. Mitigation measures such as fishways, have been increasingly implemented to restore river connectivity and support fish migration.
Paolo Moccetti, Jamie R. Dodd, Domino A. Joyce, Andy D. Nunn, Ben Gillespie, Jonathan D. Bolland   +5 more
doaj   +1 more source

Genetic Limitation and Conservation Implications in Tetracentron sinense: SNP-Based Analysis of Spatial Genetic Structure and Gene Flow

Biology
The present research investigates the fine-scale spatial genetic structure (SGS) and gene flow dynamics in the endangered relict tree Tetracentron sinense, a keystone species in China’s montane ecosystems facing severe habitat fragmentation and genetic ...
Xiaojuan Liu, Xue Wang, Hongyan Han, Ting Pan, Mengxing Jia, Xiaohong Gan   +5 more
doaj   +1 more source