Results 41 to 50 of about 1,189,577 (306)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Retention of neutral genetic diversity and connectivity within the metapopulation of Florida Scrub-Jay at Kennedy Space Center

open access: yesJournal of Field Ornithology
Habitat specialists, impacted by anthropogenic land modification, are often of great conservation concern. Florida Scrub-Jays ( Aphelocoma coerulescens ) are threatened, scrub-endemic birds primarily found in small, isolated patches where they have a ...
Cory J Spern   +4 more
doaj   +1 more source

Fitness and Rhizobacteria of F2, F3 Hybrids of Herbicide-Tolerant Transgenic Soybean and Wild Soybean

open access: yesPlants, 2022
The introduction of herbicide-tolerant (HT) transgenic soybeans (Glycine max (L.) Merr.) into farming systems raises great concern that transgenes may flow to endemic wild soybeans (Glycine soja Sieb.
Rong Liang   +5 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Microsatellite-Based Genetic Structure and Diversity of Local Arabian Sheep Breeds

open access: yesFrontiers in Genetics, 2018
The genetic diversity of the sheep breeds in the Arab countries might be considered to be a mirror of the ecology of the region. In this study, the genetic structure and diversity of sheep breeds from Saudi Arabia (Harri, Najdi, Naemi, Arb, and Rufidi ...
Raed M. Al-Atiyat   +4 more
doaj   +1 more source

Opportunities and inherent limits of using environmental DNA for population genetics

open access: yesEnvironmental DNA, 2023
Molecular techniques using DNA retrieved from community or environmental samples, in particular environmental DNA (eDNA), are becoming increasingly popular for detecting individual species, assessing biodiversity, and quantifying ecological indices. More
Marjorie Couton   +2 more
doaj   +1 more source

Multi-Locus Sequence Analysis Reveals the Genetic Diversity and Population Differentiation of Candidatus Liberibacter Asiaticus in China

open access: yesDiversity, 2023
Huanglongbing (HLB) is a devastating citrus disease caused by Candidatus Liberibacter asiaticus (CLas). Since its initial outbreak in Guangdong Province, China, it has spread to 10 provinces and caused significant economic losses.
Ping You   +6 more
doaj   +1 more source

GENE FLOW AND SELECTION IN A CLINE [PDF]

open access: yesGenetics, 1973
ABSTRACT A model of the effect of gene flow and natural selection in a continuously distributed, infinite population is developed. Different patterns of spatial variation in selective pressures are considered, including a step change in the environment, a "pocket" in the environment and a periodically varying environment.
openaire   +2 more sources

Inteins as indicators of gene flow in the halobacteria [PDF]

open access: yesFrontiers in Microbiology, 2014
This research uses inteins, a type of mobile genetic element, to infer patterns of gene transfer within the Halobacteria. We surveyed 118 genomes representing 26 genera of Halobacteria for intein sequences. We then used the presence-absence profile, sequence similarity and phylogenies from the inteins recovered to explore how intein distribution can ...
Soucy, Shannon M.   +3 more
openaire   +3 more sources

Paternity analysis of pollen-mediated gene flow for Fraxinus excelsior L. in a chronically fragmented landscape [PDF]

open access: yes, 2008
Paternity analysis based on microsatellite marker genotyping was used to infer contemporary genetic connectivity by pollen of three population remnants of the wind-pollinated, wind-dispersed tree Fraxinus excelsior, in a deforested Scottish landscape. By
Bacles, Cecile F E   +3 more
core   +1 more source

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