Results 61 to 70 of about 1,189,577 (306)

A theory of measuring natural selection and genetic monitoring

open access: yesCommunicative & Integrative Biology
Two methods have been compared for determining the value of natural selection in the natural populations. The first method, based on the FST-statistics, employs the dependence of genetic diversity of a species on the value of gene flow between ...
A. I. Yuriev
doaj   +1 more source

A model of pollinator-mediated gene flow between plant populations with numerical solutions for bumblebees pollinating oilseed rape

open access: yes, 2002
We present a model that predicts the level of gene flow mediated by animal pollinators from a source population to a sink population. The model requires specification of three elements: (1) the paternity that originates from a single flower, the ...
Osborne, J. L.   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Genetic consequences of improved river connectivity in brown trout (Salmo trutta L.)

open access: yesEvolutionary Applications
Fragmentation of watercourses poses a significant threat to biodiversity, particularly for migratory fish species. Mitigation measures such as fishways, have been increasingly implemented to restore river connectivity and support fish migration.
Paolo Moccetti   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Component parts of the World Heat Flow Data Collection

open access: yes, 1968
Component parts of the World Heat Flow Data ...
Ki-Iti Horai (7990757)   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fine scale gene flow and individual movements among subpopulations of Centrolene prosoblepon (Anura: Centrolenidae)

open access: yesRevista de Biología Tropical, 2008
Dispersal capabilities determine and maintain local gene flow, and this has implications for population persistence and/or recolonization following environmental perturbations (natural or anthropogenic), disease outbreaks, or other demographic collapses.
Jeanne M Robertson   +2 more
doaj  

The effect of patch size and separation on bumblebee foraging in oilseed rape: implications for gene flow

open access: yes, 2004
1. Theory predicts that the susceptibility of patches of plants to gene flow mediated by incoming pollinators will depend on the length of pollinator residence (the number of flowers visited during a bout in a patch).
Osborne, J. L., Cresswell, J. E.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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