Results 81 to 90 of about 1,973,564 (301)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pollen production and dispersion in Pinus roxburghii [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2019
Pollen dispersion and frequency of flowering were studied in the natural population of Pinus roxburghii Sargent (Chir pine) at altitudes between 1600 and 1900 m above sea level in the Tehri forest division of Garhwal Himalaya.
Vinod Prasad Khanduri
doaj   +1 more source

Extracting Functional Modules from Biological Pathways [PDF]

open access: yes, 2007
It has been proposed that functional modules are the fundamental units of cellular function. Methods to identify these modules have thus far relied on gene expression data or protein-protein interaction (PPI) data, but have a few limitations.
Sihai D. Zhao, Yong Li
core   +3 more sources

Butterfly gene flow goes berserk [PDF]

open access: yesGenome Biology, 2016
A new study shows that genomic introgression between two Heliconius butterfly species is not solely confined to color pattern loci.
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

ISSR-PCR markers for assessment of genetic diversity in some Iranian and foreign grape cultivars (Vitis vinifera L.)

open access: yesEuropean Journal of Horticultural Science
With the rise in planting new grape varieties, accurate identification and ensuring plant authenticity are crucial, as mistakes can cause significant financial losses in wine and table grape production.
Rasool Molaie   +3 more
doaj   +1 more source

GENE FLOW AND GENETIC DIFFERENTIATION [PDF]

open access: yesGenetics, 1974
ABSTRACT A brief analysis is presented for the effects of gene flow upon genetic differentiation within and between populations generated by mutation and drift. Previous results obtained with the "island" model are developed into a form that lends itself to biological interpretation.
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gene Flow in Genetically Modified Wheat

open access: yesPLoS ONE, 2011
Understanding gene flow in genetically modified (GM) crops is critical to answering questions regarding risk-assessment and the coexistence of GM and non-GM crops. In two field experiments, we tested whether rates of cross-pollination differed between GM and non-GM lines of the predominantly self-pollinating wheat Triticum aestivum.
Rieben, Silvan   +3 more
openaire   +5 more sources

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