Results 161 to 170 of about 1,973,564 (301)

Latitudinal Clines in Gene Flow and Demographic Stability Reveal Drivers of Microendemism in a Radiation of Alpine Grasshoppers. [PDF]

Mol Ecol
Ortego J, Trillo M, Gutiérrez-Rodríguez J, García-Navas V.   +3 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Lack of Population Structure of an Extreme Migratory Shorebird: Evidence of Gene Flow Between Geographically Disparate Populations. [PDF]

Ecol Evol
Gherardi-Fuentes C, Ruiz J, Senner NR, Johnson JA, Masero JA, Gutiérrez J, Verdugo C, Navedo JG.   +7 more
europepmc   +1 more source

Mitochondrial gene flow

Mitochondrial gene flow
To account for the transmission of mitochondrial DNA between conspecific species Drosophila pseudoobscura and D. persimilis in sympatry reported by J.R. Powell, a simple model of gene flow and selection in infinite populations is analyzed. The model assumes two alleles at each of two loci, one of which is coded by an autosome and the other by ...
openaire  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Staphylococcal phages as agents of evolution and innovation: From gene flow to next-generation therapeutics. [PDF]

Genet Mol Biol
Rossi CC, Teixeira FCOB, Silva GCD, Pereira MF, Giambiagi-deMarval M.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Habitat Mosaic Limits Gene Flow and Promotes Morphological Adaptation in a Generalist Mammal. [PDF]

Ecol Evol
Booth W, Montgomery WI, Miles LS, Montgomery SH, Harrod C, Schunke A, Prodöhl PA.   +6 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Gene Flow and Habitat Heterogeneity Shape Coexistence Dynamics of Arctic Charr Morphs in Connected Lakes. [PDF]

Mol Ecol
Xiao H, Pálsson A, Jónsson ZO, Snorrason SS.   +3 more
europepmc   +1 more source