Results 201 to 210 of about 1,973,564 (301)

Submerged Corridors of Ancient Gene Flow in an Island Amphibian. [PDF]

Mol Ecol
Sherlock MB, Wilkinson M, Maddock ST, Nussbaum RA, Day JJ, Streicher JW.   +5 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Phylogeny-aware Simulations Suggest a Low Impact of Unsampled Lineages in the Inference of Gene Flow During Eukaryogenesis. [PDF]

Genome Biol Evol
Bernabeu M, Manzano-Morales S, Gabaldón T.   +2 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Population structure, gene flow and genetic diversity of sheep blowfly (Lucilia cuprina dorsalis) in Australia. [PDF]

BMC Genomics
Kapoor S, Young ND, Jex AR, Baxter S, Yang YT, Davies AJ, Armstrong MN, Whiteside TL, Batterham P, Gasser RB, Bowles VM, Perry T, Anstead CA.   +12 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Sex Differentiation and Long-Distance Gene Flow in the Elusive Antarctic Fish <i>Aethotaxis mitopteryx</i>. [PDF]

Ecol Evol
Schiavon L, Desvignes T, Ronco F, Matschiner M, Gastaldi M, Koppetsch T, Schrøder-Nielsen A, Postlethwait JH, Prestanti A, Stranci F, Ceballos SG, Mark FC, Lucassen M, Riginella E, La Mesa M, Papetti C.   +15 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Contrasting Evolutionary Trajectories: Differential Population Dynamics and Gene Flow Patterns in Sympatric <i>Halimeda discoidea</i> and <i>Halimeda macroloba</i>. [PDF]

Biology (Basel)
Tong Y, Liu W, Sun Y, Liu J, Yang Q.
europepmc   +1 more source