Results 231 to 240 of about 1,973,564 (301)

Inference of Gene Flow between Species from Genomic Data When the Mode, Direction, and Lineages are Misspecified. [PDF]

Mol Biol Evol
Thawornwattana Y, Flouri T, Mallet J, Yang Z.   +3 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Genomic Data Reveal Multiple Introduction Sources and Limited Post-Colonization Gene Flow in Southeast Michigan Invasive Red Swamp Crayfish (<i>Procambarus clarkii</i>). [PDF]

Ecol Evol
Adams NE, Homola JJ, Sard NM, Nathan LR, Roth BM, Robinson JD, Scribner KT.   +6 more
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Host-Associated Genetic Differentiation in the Face of Ongoing Gene Flow: Ecological Speciation in a Pathogenic Parasite of Freshwater Fish. [PDF]

Mol Biol Evol
Nazarizadeh M, Nováková M, Vlček J, Štefka J.   +3 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Pangenome analysis reveals yield- and fiber-related diversity and interspecific gene flow in Gossypium barbadense L. [PDF]

Nat Commun
Meng Q, Xie P, Xu Z, Tang J, Hui L, Gu J, Gu X, Jiang S, Rong Y, Zhang J, Udall JA, Grover CE, Zheng K, Chen Q, Kong J, Wang M, Nie X, Lin Z, Jin S, Wendel JF, Zhang X, Yuan D.   +21 more
europepmc   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population. [PDF]

Commun Biol
Dussex N, Jansson I, van der Valk T, Packer C, Norman A, Kissui BM, E Mjingo E, Spong G.   +7 more
europepmc   +1 more source