Results 251 to 260 of about 1,855,658 (333)

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Genetic Differentiation is Constrained to Chromosomal Inversions and Putative Centromeres in Locally Adapted Populations With Higher Gene Flow. [PDF]

Mol Biol Evol
Akopyan M, Tigano A, Jacobs A, Wilder AP, Therkildsen NO.   +4 more
europepmc   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

No detectable effect of urbanization on genetic drift or gene flow in specialist herbivorous insects of milkweed. [PDF]

PLoS One
Miles LS, Carlen EJ, Nassrullah Z, Munshi-South J, Johnson MTJ.   +4 more
europepmc   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Genomic regions of current low hybridisation mark long-term barriers to gene flow in scarce swallowtail butterflies. [PDF]

PLoS Genet
Ebdon S, Laetsch DR, Vila R, Baird SJE, Lohse K.   +4 more
europepmc   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Gene Flow Across Large Distances in the Cavity-Nesting Wasp <i>Deuteragenia subintermedia</i> in a Central European Forest. [PDF]

Ecol Evol
Ruppert LS, Staab M, Rappa NJ, Frey J, Segelbacher G.   +4 more
europepmc   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Regional antimicrobial resistance gene flow among the One Health sectors in China. [PDF]

Microbiome
Feng Y, Lu X, Zhao J, Li H, Xu J, Li Z, Wang M, Peng Y, Tian T, Yuan G, Zhang Y, Liu J, Zhang M, Zhu La AT, Qu G, Mu Y, Guo W, Wu Y, Zhang Y, Wang D, Hu Y, Kan B.   +21 more
europepmc   +1 more source