Results 191 to 200 of about 3,986,989 (305)

Uterine mesenchymal tumour with a novel EWSR1::CTBP1 gene fusion. [PDF]

Virchows Arch
Bode-Lesniewska B, Illigen F, Matter MS.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

A <i>CLIP</i> on the Ear: Spitz Melanocytoma Harbouring a <i>CLIP2-BRAF</i> Gene Fusion. [PDF]

Case Rep Dermatol Med
Moutasim KA, Atweh M, Theaker JM.
europepmc   +1 more source

Precise gene fusion by PCR

Nucleic Acids Research, 1989
J, Yon, M, Fried
openaire   +3 more sources

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

An epithelioid hemangioendothelioma with a novel RREB1::TFE3 gene fusion. [PDF]

Virchows Arch
Schumacher T, Ameline B, Vogetseder A, Bode B, Svantesson T.   +4 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Myoepithelial Tumor of Soft Tissue With the Novel IRF2BP2::CDX1 Gene Fusion. [PDF]

Cureus
Naous R, Diaz-Aragon R, Karunamurthy A.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Salivary Oncocytic Intraductal Carcinoma of Harboring a Novel GAB1::FRK Gene Fusion. [PDF]

Head Neck Pathol
Whaley RD, Hofich CD, Halling KC, Pitel BA.   +3 more
europepmc   +1 more source