Results 151 to 160 of about 806,287 (306)
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Building Scarless Gene Libraries in the Chromosome of Bacteria
Dorrazehi, Gol Mohammad +5 more
openaire +2 more sources
The exhibition was held in the Rare Books Exhibition space, Sir Louis Matheson Library, Monash University from 27 March - 5 June 2014.Opening address given by Gene Bawden, Deputy Head, Design (Communication Design), Faculty of Art Design and Architecture,
core
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian +7 more
wiley +1 more source
Cloning a Novel Metallophosphoesterase Gene from a Kidney Cdna Library of Hypertensive Rat
Background and purpose: Genetic and environmental factors may contribute to the pathogenesis of essential hypertension . To facilitate genetic studies of hypertension and renal disorders, we sought to clone novel genes from a modified, equalized kidney ...
CHERN, TSER-HAW;CHIANG, FU-TIEN;HSU, KWAN-LIH;LO, HUEY-MING;TSENG, CHUEN-DEN;TSENG, YUNG-ZU +1 more
core
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Scalable and cost-efficient custom gene library assembly from oligopools. [PDF]
Freschlin CR, Yang KK, Romero PA.
europepmc +1 more source
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source

