Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
The cytochrome oxidases ofBacillus subtilis: mapping of a gene affecting cytochromeaa3and its replacement by cytochromeoin a mutant strain [PDF]
William James+3 more
openalex +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Mapping of the supP ( Su6 + ) Amber Suppressor Gene in Escherichia coli [PDF]
Ástrós Arnardóttir+2 more
openalex +1 more source
Gene mapping and functional annotation of GWAS of oral ulcers using FUMA software. [PDF]
Jin X+5 more
europepmc +1 more source
Using Breeding Populations With a Dual Purpose: Cultivar Development and Gene Mapping-A Case Study Using Resistance to Common Bacterial Blight in Dry Bean (Phaseolus vulgaris L.). [PDF]
Simons KJ+6 more
europepmc +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Nucleotide Sequence and Chromosomal Mapping of the Human c‐yes‐2 Gene [PDF]
Kentaro Semba+8 more
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source