Results 51 to 60 of about 600,813 (339)

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

FEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri, Haruka Tachibana, Daisuke Kawasaki, Taichi Chisuga, Toma Kashima, Shinya Fushinobu, Fumitaka Kudo, Tadashi Eguchi, Akimasa Miyanaga   +8 more
wiley   +1 more source

Gene mapping and candidate gene analysis of aberrant-floral spikelet 1 (afs1) in rice (Oryza sativa L.)

Journal of Integrative Agriculture, 2020
The spikelet is a unique inflorescence structure in grasses. However, the molecular mechanism that regulates its development remains unclear, and we therefore characterize a spikelet mutant of rice (Oryza sativa L.), aberrant-floral spikelet 1 (afs1 ...
Ting ZHANG, Jing YOU, Guo-ling YU, Yi ZHANG, Huan CHEN, Yi-dan LI, Li YE, Wan-yue YAO, Yu-jie TU, Ying-hua LING, Guang-hua HE, Yun-feng LI   +11 more
doaj  

Loss-of-Function of a Tomato Receptor-Like Kinase Impairs Male Fertility and Induces Parthenocarpic Fruit Set

Frontiers in Plant Science, 2019
Parthenocarpy arises when an ovary develops into fruit without pollination/fertilization. The mechanisms involved in genetic parthenocarpy have attracted attention because of their potential application in plant breeding and also for their elucidation of
Hitomi Takei, Hitomi Takei, Yoshihito Shinozaki, Yoshihito Shinozaki, Ryoichi Yano, Sachiko Kashojiya, Michel Hernould, Michel Hernould, Christian Chevalier, Hiroshi Ezura, Hiroshi Ezura, Tohru Ariizumi, Tohru Ariizumi   +12 more
doaj   +1 more source

Identification of Rice Aromatic Compounds by Solid Phase Micro-Extraction method in GC-MS and Mapping their Controlling QTLs using Microsatellite Marker [PDF]

مجله بیوتکنولوژی کشاورزی, 2013
Increasing demand for aromatic rice causes their higher price and attracted plant breeder's attention to recognize rice aroma-controlling genes. Highly linked markers with the genes controlling important agronomic traits help to make phenotypic selection,
Reza Amiri Fahliyani, Mahmoud Khodambashi, Alireza Ghiyasvand   +2 more
doaj   +1 more source

Gene tree reconciliation including transfers with replacement is hard and FPT [PDF]

, 2017
Phylogenetic trees illustrate the evolutionary history of genes and species. In most cases, although genes evolve along with the species they belong to, a species tree and gene tree are not identical, because of evolutionary events at the gene level like duplication or transfer.
arxiv   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

The Sorghum Gene for Leaf Color Changes upon Wounding (P) Encodes a Flavanone 4-Reductase in the 3-Deoxyanthocyanidin Biosynthesis Pathway

G3: Genes, Genomes, Genetics, 2016
Upon wounding or pathogen invasion, leaves of sorghum [Sorghum bicolor (L.) Moench] plants with the P gene turn purple, whereas leaves with the recessive allele turn brown or tan.
Hiroyuki Kawahigashi, Shigemitsu Kasuga, Yuji Sawada, Jun-ichi Yonemaru, Tsuyu Ando, Hiroyuki Kanamori, Jianzhong Wu, Hiroshi Mizuno, Mitsuru Momma, Zui Fujimoto, Masami Yokota Hirai, Takashi Matsumoto   +11 more
doaj   +1 more source

Integration of Differential Gene-combination Search and Gene Set Enrichment Analysis: A General Approach [PDF]

arXiv, 2011
Gene Set Enrichment Analysis (GSEA) and its variations aim to discover collections of genes that show moderate but coordinated differences in expression. However, such techniques may be ineffective if many individual genes in a phenotype-related gene set have weak discriminative power.
arxiv  

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Statistical Approaches to Gene Mapping [PDF]

The American Journal of Human Genetics, 2000
In this brief primer, we hope to provide a general overview on statistical methods for disease-gene mapping. Of course, this cannot be complete—our apologies to researchers whose methods are not mentioned below. More-detailed information may be found in relevant textbooks (Ott 1999) and at the Web Resources of Genetic Linkage Analysis site (Laboratory ...
Jurg Ott, Josephine Hoh
openaire   +3 more sources