Results 51 to 60 of about 480,706 (316)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Genetic Mapping of the Gmpgl3 Mutant Reveals the Function of GmTic110a in Soybean Chloroplast Development

Frontiers in Plant Science, 2022
The generation of oxygen and organic matter in plants mainly depends on photosynthesis, which directly affects plant growth and development. The chloroplast is the main organelle in which photosynthesis occurs.
Hui Yu, Qiushi Wang, Zhirui Zhang, Zhirui Zhang, Tao Wu, Tao Wu, Xinjing Yang, Xinjing Yang, Xiaobin Zhu, Xiaobin Zhu, Yongheng Ye, Yongheng Ye, Jiantian Leng, Suxin Yang, Xianzhong Feng, Xianzhong Feng, Xianzhong Feng   +16 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Identification of a recessive gene RgM4G52 conferring red glume, stem, and rachis in a Triticum boeoticum mutant

Frontiers in Plant Science
Anthocyanins are plant secondary metabolites belonging to the polyphenol class of natural water-soluble phytopigments. The accumulation of anthocyanins in different plant tissues can improve plant survival under adverse conditions.
Longyu Chen, Longyu Chen, Junqing Zhang, Junqing Zhang, Pan Ma, Pan Ma, Yongping Miao, Yongping Miao, Lei Wu, Lei Wu, Ke Zhou, Ke Zhou, Jiaru Yang, Jiaru Yang, Minghu Zhang, Xin Liu, Bo Jiang, Ming Hao, Lin Huang, Shunzong Ning, Xuejiao Chen, Xue Chen, Dengcai Liu, Dengcai Liu, Hongshen Wan, Hongshen Wan, Lianquan Zhang, Lianquan Zhang   +27 more
doaj   +1 more source

A Gene-Based Method for Cytogenetic Mapping of Repeat-Rich Mosquito Genomes [PDF]

, 2021
Reem A. Masri, Dmitriy A. Karagodin, Atashi Sharma, Maria V. Sharakhova   +3 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Modulations in Gene Expression and Mapping of Genes Associated with Cyst Nematode Infection of Soybean

Molecular Plant-Microbe Interactions, 2001
Infection of the soybean root by the soybean cyst nematode (SCN) (Heterodera glycines Ichinohe) induces a well-documented, yet poorly understood, response by the host plant.
Zarir Vaghchhipawala, Ronald Bassüner, Kathryn Clayton, Kimberley Lewers, Randy Shoemaker, Sally Mackenzie   +5 more
doaj   +1 more source

The Fox Gene Map [PDF]

ILAR Journal, 1998
The wild type red fox is common to Europe, Asia, North Africa, and North America. Furthermore, it has accommodated itself so well in Australia, where it was taken from England, that it has spread over the entire continent. It adapts easily to different climates and biocoenoses—in the open; in the forest, highland or lowland; on the coast; or inland. In
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source