Results 61 to 70 of about 542,125 (315)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Statistical epistasis between candidate gene alleles for complex tuber traits in an association mapping population of tetraploid potato [PDF]

, 2010
Association mapping using DNA-based markers is a novel tool in plant genetics for the analysis of complex traits. Potato tuber yield, starch content, starch yield and chip color are complex traits of agronomic relevance, for which carbohydrate metabolism
Paulo, M.J., Christiane Gebhardt, van Eeuwijk, F.A., Fred van Eeuwijk, van Eeuwijk, F., Li, Li, Maria-João Paulo, Paulo, M., Gebhardt, C., Eeuwijk, F.A., van, Li Li, Li, L.   +11 more
core   +1 more source

Progress in Genetic Studies of Tourette’s Syndrome

Brain Sciences, 2017
Tourette’s Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time.
Yanjie Qi, Yi Zheng, Zhanjiang Li, Lan Xiong   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Fine Mapping and Candidate Gene Identification for Wax Biosynthesis Locus, BoWax1 in Brassica oleracea L. var. capitata

Frontiers in Plant Science, 2018
Cuticular waxes play important roles in plant protection against various biotic and abiotic environmental stresses. The cuticular wax covering gives normal cabbage a glaucous appearance, but the appearance of waxless mutant is glossy green.
Dongming Liu, Dongming Liu, Dongming Liu, Xin Dong, Zezhou Liu, Jun Tang, Mu Zhuang, Yangyong Zhang, Honghao Lv, Yumei Liu, Zhansheng Li, Zhiyuan Fang, Limei Yang   +12 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Identification of a recessive gene RgM4G52 conferring red glume, stem, and rachis in a Triticum boeoticum mutant

Frontiers in Plant Science
Anthocyanins are plant secondary metabolites belonging to the polyphenol class of natural water-soluble phytopigments. The accumulation of anthocyanins in different plant tissues can improve plant survival under adverse conditions.
Longyu Chen, Longyu Chen, Junqing Zhang, Junqing Zhang, Pan Ma, Pan Ma, Yongping Miao, Yongping Miao, Lei Wu, Lei Wu, Ke Zhou, Ke Zhou, Jiaru Yang, Jiaru Yang, Minghu Zhang, Xin Liu, Bo Jiang, Ming Hao, Lin Huang, Shunzong Ning, Xuejiao Chen, Xue Chen, Dengcai Liu, Dengcai Liu, Hongshen Wan, Hongshen Wan, Lianquan Zhang, Lianquan Zhang   +27 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Chicken microchromosomes are hyperacetylated, early replicating, and gene rich

, 1998
The chicken karyotype consists of 39 chromosomes of which 33 are classed as microchromosomes (MICs). MICs contain about one third of genomic DNA. The majority of mapped chicken genes are assigned to macrochromosomes (MACs), but a recent study indicated ...
Heather A. McQueen, Siriaco, G, Giorgia Siriaco, Bird, A P; id_orcid, McQueen, H A; id_orcid, Adrian P. Bird   +5 more
core   +1 more source

The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services [PDF]

, 2010
BACKGROUND: Many complementary solutions are available for the identifier mapping problem. This creates an opportunity for bioinformatics tool developers.
Kelder, T.A.J., Alexander R Pico, van Iersel, Martijn P, Hanspers, K, van Iersel, M.P., Pico, A.R., Isaac Ho, Conklin, B.R., Conklin, BR, Pico, AR, Evelo, C.T.A., Kelder, T, Evelo, Chris T, Kelder, Thomas, Martijn P van Iersel, Evelo, CT, van Iersel, MP, Evelo, C.T.A.; id_orcid, Gao, J., Conklin, Bruce R, Ho, I, Thomas Kelder, Ho, I., Bruce R Conklin, Kristina Hanspers, Gao, J, Ho, Isaac, Chris T Evelo, Hanspers, Kristina, Jianjiong Gao, Pico, Alexander R, Gao, Jianjiong, Hanspers, K.   +32 more
core   +1 more source