Results 51 to 60 of about 284,816 (301)

The POU-er of gene nomenclature [PDF]

Development, 2014
The pluripotency factor POU5F1 (OCT4) is well known as a key regulator of stem cell fate. Homologues of POU5F1 exist throughout vertebrates, but the evolutionary and functional relationships between the various family members have been unclear. The level to which function has been conserved within this family provides insight into the evolution of ...
Frankenberg, Stephen R, Frank, Dale, Harland, Richard, Johnson, Andrew D, Nichols, Jennifer, Niwa, Hitoshi, Schöler, Hans R, Tanaka, Elly, Wylie, Chris, Brickman, Joshua M   +9 more
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Functional and Immunological Relevance of Anaplasma marginale Major Surface Protein 1a Sequence and Structural Analysis. [PDF]

, 2013
Bovine anaplasmosis is caused by cattle infection with the tick-borne bacterium, Anaplasma marginale. The major surface protein 1a (MSP1a) has been used as a genetic marker for identifying A.
Cabezas-Cruz, Alejandro, de la Fuente, José, Estrada-Peña, Agustín, Ferrolho, Joana, Grubhoffer, Libor, Kenneil, Rachel, Kocan, Katherine M., Lis, Katarzyna, Passos, Lygia M. F., Pohl, Anna E., Ribeiro, Mucio F. B., Shkap, Varda, Tonk, Miray, Valdés, James J., Zweygarth, Erich   +14 more
core   +10 more sources

p63 in Mytilus galloprovincialis and p53 family members in the phylum Mollusca [PDF]

, 2009
Genes of the p53 family are known to be critical regulators of the cell cycle. They have already been established as possible biomarkers. Elaborate regulation mechanisms result in numerous cDNA and protein isoforms being expressed from each gene of the ...
Baričević, Ana, Batel, Renato, Blašković, Sanja, Mičić, Milena, Ramšak, Andreja, Zahn, Rudolf K., Štifanić, Mauro   +6 more
core   +1 more source

Guidelines for Human Gene Nomenclature

Genomics, 2002
Guidelines for human gene nomenclature were first pub-lished in 1979 [1], when the Human Gene NomenclatureCommittee was first given the authority to approve andimplement human gene names and symbols. Updates of theseguidelines were published in 1987 [2], 1995 [3], and 1997 [4].With the recent publications of the complete human genomesequence there is ...
Hester M, Wain, Elspeth A, Bruford, Ruth C, Lovering, Michael J, Lush, Mathew W, Wright, Sue, Povey   +5 more
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases

Journal of Lipid Research, 2005
Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA esters such as acyl-CoAs (saturated, unsaturated, branched-chain), bile acid-CoAs, CoA esters of prostaglandins, etc., to the corresponding free acid and
Mary C. Hunt, Junji Yamada, Lois J. Maltais, Mathew W. Wright, Ernesto J. Podesta, Stefan E.H. Alexson   +5 more
doaj   +1 more source

An approach for proteins and their encoding genes synonyms integration based on protein ontology

BMC Bioinformatics, 2023
Background Biological research is generating high volumes of data distributed across various sources. The inconsistent naming of proteins and their encoding genes brings great challenges to protein data integration: proteins and their coding genes ...
Xiaohong Wang, Xiaoli Jing, Fangkun Dou, Haowei Cao   +3 more
doaj   +1 more source