Results 101 to 110 of about 7,457,987 (378)

The Plant Ontology: A common reference ontology for plants [PDF]

, 2010
The Plant Ontology (PO) (http://www.plantontology.org) (Jaiswal et al., 2005; Avraham et al., 2008) was designed to facilitate cross-database querying and to foster consistent use of plant-specific terminology in annotation.
Chris, Mungall, Cooper Laurel, D., Gandolfo Maria, A., Justin, Elser, Pankaj, Jaiswal, Smith, Barry, Stevenson Dennis, W., Walls Ramona, L.   +7 more
core  

Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance [PDF]

, 2013
Alfredo Ghezzi, Harish R. Krishnan, Linda Lew, Francisco J. Prado III, Darryl S. Ong, Nigel S. Atkinson, Section of Neurobiology and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas, United States of ...
Atkinson, Nigel S., Ghezzi, Alfredo, Krishnan, Harish R., Lew, Linda, Ong, Darryl S., Prado III, Francisco J.   +5 more
core   +3 more sources

The Gene Ontology and the Meaning of Biological Function.

Methods in molecular biology, 2017
The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms. It is specifically designed for supporting the computational representation of biological systems.
P. Thomas
semanticscholar   +1 more source

Gene-Ontology-based clustering of gene expression data [PDF]

Bioinformatics, 2004
Abstract Summary: The expected correlation between genetic co-regulation and affiliation to a common biological process is not necessarily the case when numerical cluster algorithms are applied to gene expression data. GO-Cluster uses the tree structure of the Gene Ontology database as a framework for numerical clustering, and thus ...
Adryan, B., Schuh, R.
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A gene-phenotype network for the laboratory mouse and its implications for systematic phenotyping.

PLoS ONE, 2011
The laboratory mouse is the pre-eminent model organism for the dissection of human disease pathways. With the advent of a comprehensive panel of gene knockouts, projects to characterise the phenotypes of all knockout lines are being initiated.
Octavio Espinosa, John M Hancock
doaj   +1 more source

Assembly of an interactive correlation network for the Arabidopsis genome using a novel heuristic clustering algorithm [PDF]

, 2010
Peer reviewedPublisher ...
Ebenhoeh, Oliver, Loraine, Ann, Mutwil, Marek, Persson, Staffan, Schütte, Moritz, Usadel, Björn   +5 more
core   +2 more sources

Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations

Scientific Reports, 2017
Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments.
Aurelie Tomczak, J. Mortensen, R. Winnenburg, Charles Liu, Dominique T. Alessi, Varsha Swamy, Francesco Vallania, Shane Lofgren, W. Haynes, N. Shah, M. Musen, P. Khatri   +11 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Discovering gene annotations in biomedical text databases

BMC Bioinformatics, 2008
Background Genes and gene products are frequently annotated with Gene Ontology concepts based on the evidence provided in genomics articles. Manually locating and curating information about a genomic entity from the biomedical literature requires vast ...
Ozsoyoglu Gultekin, Cakmak Ali
doaj   +1 more source