Results 101 to 110 of about 347,215 (296)

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Evaluating Computational Gene Ontology Annotations [PDF]

open access: yes, 2016
ISBN:978-1-4939-3743 ...
Škunca, Nives   +2 more
openaire   +4 more sources

Quantifying literature citations, index terms, and Gene Ontology annotations in the Saccharomyces Genome Database to assess results-set clustering utility [PDF]

open access: yes, 2006
A set of 37,325 unique literature citations was identified from 120,078 literature-based annotations in the Saccharomyces Genome Database (SGD). The citations, gene products, and related Gene Ontology (GO) annotations were analyzed to quantify unique ...
MacMullen, W. John
core  

A Bayesian Hierarchical Model to Derive Novel Gene Networks from Gene Ontology Fingerprints

open access: yes, 2009
We developed a Bayesian hierarchical model to identify gene networks based on the similarity score generated from comparing the gene ontology fingerprints of gene pairs.
Lam Tsoi   +3 more
core   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

SORGOdb: Superoxide Reductase Gene Ontology curated DataBase

open access: yesBMC Microbiology, 2011
Background Superoxide reductases (SOR) catalyse the reduction of superoxide anions to hydrogen peroxide and are involved in the oxidative stress defences of anaerobic and facultative anaerobic organisms.
Salbert Gilles   +4 more
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

The Gene Ontology Resource: 20 years and still GOing strong.

open access: yes, 2020
The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products.
The Gene Ontology Consortium (9573080)   +1 more
core  

Building an Advance Domain Ontology Model of Information Science (OIS)

open access: yes, 2014
The paper describes the process of modelling domain knowledge of Information Science (IS) by creating an Ontology of Information Science domain (OIS).
Lu, Joan   +3 more
core   +1 more source

Semantics in Support of Biodiversity Knowledge Discovery: An Introduction to the Biological Collections Ontology and Related Ontologies [PDF]

open access: yes, 2014
The study of biodiversity spans many disciplines and includes data pertaining to species distributions and abundances, genetic sequences, traitmeasurements, and ecological niches, complemented by information on collection and measurement protocols.
Midford, Peter E.   +91 more
core   +1 more source

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