Results 131 to 140 of about 463,290 (301)
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Testing for treatment effects on gene ontology
BMC Bioinformatics, 2008 In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functional category such as gene ontology terms (GO terms, http://www ...
Delongchamp Robert R +4 more
doaj +1 more source
A New Hierarchical Redundancy Eliminated Tree Augmented Naive Bayes Classifier for Coping with Gene Ontology-based Features [PDF]
, 2016 The Tree Augmented Naive Bayes classifier is a type of probabilistic graphical model that can represent some feature dependencies. In this work, we propose a Hierarchical Redundancy Eliminated Tree Augmented Naive Bayes (HRE-TAN) algorithm, which ...
Freitas, Alex A., Wan, Cen
core +2 more sources
Advanced Healthcare Materials, EarlyView.Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu +10 more
wiley +1 more source
From Affective Science to Psychiatric Disorder: Ontology as Semantic Bridge [PDF]
, 2018 Advances in emotion and affective science have yet to translate routinely into psychiatric research and practice. This is unfortunate since emotion and affect are fundamental components of many psychiatric conditions.
Hastings, Janna +1 more
core
Visualizing Gene Ontology annotations
, 2016 to appear in the forthcoming book "The Gene Ontology Handbook" (Springer Humana, ISBN 978-1-4939-3741-7)
Supek, Fran, Škunca, Nives
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum +5 more
wiley +1 more source
Gene Ontology Database Archive
, 2022 Dan Foreman-Mackey; Adrian Price-Whelan; Will Vousden; Geoffrey Ryan; Matt Pitkin; Víctor Zabalza; jsheyl; Arfon Smith; Gregory Ashton; Leo Singer; Michael Smith; Emily Rice; Adrien Deline; Alex Nitz; Brendon J. Brewer; Brigitta Sipőcz; David W. Hogg; Eric Gentry; Hanno Rein; Hennadii Madan; Ian Czekala; Jack Miller; James Matthews; James Tocknell ...
openaire +1 more source
Advanced Healthcare Materials, EarlyView.The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti +27 more
wiley +1 more source