Results 191 to 200 of about 463,290 (301)

Genetics of ovulatory dysfunction and infertility: a scoping review and gene ontology analysis. [PDF]

Front Endocrinol (Lausanne)
DiPietro EE, Sarasua SM, Hopkins CS, Ganakammal SR, Boccuto L, Hurwitz J.   +5 more
europepmc   +1 more source

DGH-GO: dissecting the genetic heterogeneity of complex diseases using gene ontology. [PDF]

BMC Bioinformatics, 2023
Asif M, Martiniano HFMC, Lamurias A, Kausar S, Couto FM.   +4 more
europepmc   +1 more source

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Structural Changes in Gene Ontology Reveal Modular and Complex Representations of Biological Function. [PDF]

Mol Biol Evol
Valverde S, Vidiella B, Martínez-Redondo GI, Duran-Nebreda S, Fernández R, Bombarely A, Rojas AM, Bentley RA.   +7 more
europepmc   +1 more source

Microbial Gene Ontology informed deep neural network for microbe functionality discovery in human diseases. [PDF]

PLoS One, 2023
Liu Y, Zhang YZ, Imoto S.
europepmc   +1 more source

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

Advanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li, Yuxin Wu, Shuai Zhou, Peipei Tang, Jiaming Wei, Ling Liu, Zhenyi Wang, Deyang Shi, Shengnan Yuan, Qingyu Zhang, Shihui Wang, Qing Zhang, Huan Zhao, Rui Zhang, Yingying Wang, Shiwei Yang, Xiangli Chen, Xiaojing Shi, Guangzhi Liu, Yuwei Zhang, Jinming Li, Xu Dong Zhang, Rick F Thorne, Dongping Wei, Zumin Zhu, Song Chen   +25 more
wiley   +1 more source

Genome-scale prediction of gene ontology from mass fingerprints reveals new metabolic gene functions. [PDF]

Life Sci Alliance
Vavricka CJ, Mochizuki M, Yuzawa S, Murata M, Yoshida T, Watanabe N, Nakatsui M, Ishii J, Hara KY, Alper HS, Hasunuma T, Kondo A, Araki M.   +12 more
europepmc   +1 more source

SSLpheno: a self-supervised learning approach for gene-phenotype association prediction using protein-protein interactions and gene ontology data. [PDF]

Bioinformatics, 2023
Bi X, Liang W, Zhao Q, Wang J.
europepmc   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

POSA-GO: Fusion of Hierarchical Gene Ontology and Protein Language Models for Protein Function Prediction. [PDF]

Int J Mol Sci
Liu Y, Wang B, Yan B, Jiang H, Dai Y.
europepmc   +1 more source