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Automating the construction of gene ontologies [PDF]

Nature Biotechnology, 2013
Manual curation of biological ontologies is recapitulated by an algorithmic approach, supplementing the Gene Ontology and enabling the discovery of relationships among genes and proteins.
David Botstein, Kara Dolinski
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Methods for Gene Ontology Annotation [PDF]

, 2007
The Gene Ontology (GO) is an established dynamic and structured vocabulary that has been successfully used in gene and protein annotation. Designed by biologists to improve data integration, GO attempts to replace the multiple nomenclatures used by specialised and large biological knowledgebases.
Emily Dimmer, Tanya Z. Berardini, Daniel Barrell, Evelyn Camon   +3 more
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Is Wikipedia a Latent Gene Ontology?

2017 IEEE 26th International Conference on Enabling Technologies: Infrastructure for Collaborative Enterprises (WETICE), 2017
Despite the significant contribution from specialized ontologies and text mining methods, the evaluation of the semantic similarity of genes remains difficult because of the complex functions in which genes are involved. A less exploited resource is Wikipedia that stores more than 10400 articles about human genes: each gene name identifies the ...
Dessì, Nicoletta, Atzori, Maurizio
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Application of Gene Ontology to Gene Identification

2011
Candidate gene identification deals with associating genes to underlying biological phenomena, such as diseases and specific disorders. It has been shown that classes of diseases with similar phenotypes are caused by functionally related genes. Currently, a fair amount of knowledge about the functional characterization can be found across several ...
Bruno Tavares, Daniel Faria, Hugo P. Bastos, Catia Pesquita, Francisco M. Couto   +4 more
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The ontology of the gene ontology.

AMIA ... Annual Symposium proceedings. AMIA Symposium, 2004
The rapidly increasing wealth of genomic data has driven the development of tools to assist in the task of representing and processing information about genes, their products and their functions. One of the most important of these tools is the Gene Ontology (GO), which is being developed in tandem with work on a variety of bioinformatics databases.
Barry, Smith, Jennifer, Williams, Steffen, Schulze-Kremer   +2 more
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On ontologies for biologists: the Gene Ontology--untangling the web.

Novartis Foundation symposium, 2002
The mantra of the 'post-genomic' era is 'gene function'. Yet surprisingly little attention has been given to how functional and other information concerning genes is to be captured, made accessible to biologists or structured in a computable form. The aim of the Gene Ontology (GO) Consortium is to provide a framework for both the description and the ...
Michael Ashburner, Suzanna E. Lewis
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Gene multifunctionality scoring using gene ontology

Journal of Bioinformatics and Computational Biology, 2018
Multifunctional genes are important genes because of their essential roles in human cells. Studying and analyzing multifunctional genes can help understand disease mechanisms and drug discovery. We propose a computational method for scoring gene multifunctionality based on functional annotations of the target gene from the Gene Ontology. The method is
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Generative adversarial learning for optimizing ontology alignment

Expert Systems, 2023
Xingsi Xue
exaly  

Specifying who delivers behaviour change interventions: development of an Intervention Source Ontology

Wellcome Open Research, 2021
Emma Norris, Alison J Wright, Janna Hastings   +2 more
exaly