Results 91 to 100 of about 3,013,569 (257)

Аldosterone synthetase gene (CYP11B2) polymorphism and structural parameters of the left ventricle in patients with coronary heart disease, postinfarction cardiosclerosis

Zaporožskij Medicinskij Žurnal, 2017
Purpose of the work – to investigate the possible contribution of aldosterone synthetase gene (CYP11B2) polymorphism to the disease course and structural parameters of LV in patients with coronary heart disease, postinfarction cardiosclerosis ...
M. N. Dolzhenko, V. Ye. Dosenko, L. Ye. Lobach   +2 more
doaj   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

HETEROGENITY OF PRIMARY BLOOD HYPERTENSION RISK FACTORS IN CHILDREN AND ADOLESCENTS

Педиатрическая фармакология, 2006
The development of diagnostic and treatment methods used for blood hypertension and its’ complications is a crucial concern of pediatrics. The study included 229 children, the study group consisted of 113 children (60 boys, 53 girls) with elevated blood ...
O.L. Kolobova
doaj   +2 more sources

The relation between protein Z polymorphism and the risk of thrombosis in Egyptian patients with antiphospholipid syndrome

Hematology/Oncology and Stem Cell Therapy, 2018
Background: The genetic background plays an important role in thrombosis and pregnancy morbidities. Low levels of protein Z is associated with increased risk of thrombosis.
Yomna K. Eissa, Hend N. Ellithy, Sherif M. Yousry, Zakaria Ismail   +3 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

BDKRB2 GENE -9/+9 POLYMORPHISM AND SWIMMING PERFORMANCE [PDF]

, 2014
The aim of the study was to evaluate the association between swimming performance and the -9/+9 (rs5810761) polymorphism within the BDKRB2 gene in successful competitive swimmers.Best individual swimming results expressed in FINA points achieved at short,
A. Leońska-Duniec, P. Cięszczyk, P. Zmijewski, A. Grenda   +3 more
core   +1 more source

Expression of Genetic Polymorphism of TMPRSS2 Gene (Rs12329760) in Different Ethnicities of Prostate Cancer Patients: A Case Control Study

Pakistan Armed Forces Medical Journal
Objective: To determine the frequency and clinical relevance of the TMPRSS2 gene polymorphism (rs12329760) in prostate cancer patients of different ethnicities. Study Design: Case-control study.
Saadia Sadiq, Amena Rahim, Muhammad Afzal, Sahar Ikram, Tehseen Ashraf Kohistani, Farzana Munir   +5 more
doaj   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Relationship between human platelet antigen-1 gene polymorphism and clopidogrel resistance in patients with coronary artery disease

Türk Kardiyoloji Derneği Arşivi, 2013
Objectives: It has been proposed that human platelet antigen- 1 (HPA-1) gene polymorphism is associated with coronary artery disease (CAD) and affects platelet function.
İbrahim Halil Tanboğa, Mehmet Mustafa Can, Alper Özkan, Hacer Ceren Tokgöz, Taylan Akgün, Fatih Koca, Mustafa Kurt, Cihangir Kaymaz   +7 more
doaj   +1 more source