Results 271 to 280 of about 758,578 (355)

<i>ALKBH5</i> gene polymorphisms and Wilms tumour susceptibility in children from East China: a case-control study. [PDF]

BMJ Paediatr Open
Yu J, Wang Y, Zhang S, Zhou H, He S, Hua R, Li W, Zhou C, Lu H.   +8 more
europepmc   +1 more source

Gene Polymorphisms Play an Important Role in the Drug Interaction Between Posaconazole and Tacrolimus in Renal Transplant Patients

Nan Hu, Mengmeng Guan, Bin Gu, Xuping Yang, Qing Qian, Di Zhao, Hui Xue, J. Jiang   +7 more
openalex   +1 more source

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

Animal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang, Wei Dai, Jiqiang Liu, Zhengguang Wang   +3 more
wiley   +1 more source

Genotypic and haplotype analysis of SOCS3 gene polymorphisms (rs4969169, rs12953258, rs1061489) in association with clinicopathological factors in breast cancer. [PDF]

BMC Med Genomics
Alipeddi RR, Padala C, Puranam K, Ulaganathan K, Neeharika RD, Sampanmudumby P, Chinta SK, Hanumanth SR.   +7 more
europepmc   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Association of Toll-like receptor signaling molecule gene polymorphisms with risk of cervical lesions in HPV-infected women. [PDF]

BMC Infect Dis
Wang S, Zhang C, Li T, Luo P, Yang Y, Lin Z, Mei B.   +6 more
europepmc   +1 more source

Genome‐Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. Methods DNA methylation profiling was analyzed in 79
Gonzalo Borrego‐Yaniz, Ana Márquez, Elkyn Estupiñán‐Moreno, Laura C. Terrón‐Camero, Miguel A. González‐Gay, Santos Castañeda, Giuliana Guggino, David Saadoun, Pietro Lio, Simona Fontana, Martina Bonacini, Alessandro Rossi, Alberto Cavazza, Francesco Muratore, Carlo Salvarani, Nicolo Pipitone, Javier Martin, Stefania Croci, Lourdes Ortiz‐Fernández   +18 more
wiley   +1 more source

Transition From Psoriasis to Psoriatic Arthritis is Characterized by Distinct Alterations in Peripheral Blood Tc17, Th17, and CD4+ Effector Memory Cells

Arthritis &Rheumatology, EarlyView.
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff, Sara Comdühr, Henry Nording, Jacob von Esebeck, Philine Letz, Miriam Prohaczka, Handan Gedik, Henner Zirpel, Elisabeth Spallek, Linh Ha‐Wissel, El‐Baraa Adjailia, Sabrina Arnold, Konstantinos Fourlakis, Sebastian Klapa, Ingo Eitel, Oliver J. Müller, Jens Y. Humrich, Gabriela Riemekasten, Diamant Thaçi, Peter Lamprecht   +19 more
wiley   +1 more source

Human melanopsin (OPN4) gene polymorphisms: a systematic review. [PDF]

Front Neurosci
Lucio-Enríquez KR, Rubio-Valles M, Ramos-Jiménez A, Pérez-León JA.   +3 more
europepmc   +1 more source