Results 261 to 270 of about 3,153,117 (306)

CYP2C19 gene polymorphism in Ningxia

Pharmacological Reports, 2023
Poor metabolizer (PM) status of CYP2C19 can be a predisposing factor for developing gastric cancer in H. pylori-infected patients. It is unclear whether PM status of CYP2C19 can also be a potential factor for H.pylori infection in healthy people.We used high-throughput sequencing to detect single nucleotide polymorphisms (SNPs) at just three loci ...
Zhen Yang, Yunqian Xie, Daya Zhang, Yan Zou, Ximei Li, Runxiang Chen, Xiaodong Zhang, Shiju Chen, Feihu Bai   +8 more
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Gene polymorphisms and behavior

Pediatric Blood & Cancer, 2007
AbstractGenetics has a entered golden post genomic era that promises to greatly improve our understanding of the etiology of complex familial disorders. Many forms of behavior are familial but Mendelian disorders are rare, and common conditions have complex inheritance.
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FOXP3 gene polymorphisms in preeclampsia

American Journal of Obstetrics and Gynecology, 2012
To determine whether polymorphisms in the FOXP3 gene are associated with preeclampsia.Case-control study in which 120 women with preeclampsia were compared with 120 healthy normotensive controls. Genetic variants (single nucleotide polymorphisms and microsatellites) in the FOXP3 gene were analyzed.
Torri D, Metz, Lesa M, Nelson, Gregory J, Stoddard, Robert M, Silver   +3 more
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Selector Genes, Polymorphisms, and Evolution

Science, 1996
Evolution has been thought to act on small changes in the characteristics of organisms coded by genes called realizator genes. D. Tautz explains how a new result in this issue of Science by Gibson and Hogness ( p. 200 ) shows that this may not always be true. A small phenotypic variation in
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Gene polymorphisms in childhood ALL

Pediatric Blood & Cancer, 2009
AbstractAcute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Inherited predisposition and exposure to exogenous leukemogenic agents have been investigated as potential risk factors. Current therapy results in 5‐year event‐free survival exceeding 80% in children in developed countries.
Nikolaos V, Karathanasis, Despoina M, Choumerianou, Maria, Kalmanti   +2 more
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Gene polymorphisms in bladder cancer

Urologic Oncology: Seminars and Original Investigations, 2008
In Europe, cancer of the bladder is the fourth most common cancer among men, accounting for 7% of total cancers. In the USA, bladder cancer is the fifth most common cancer in men and seventh in women. This disease is three times more common in men than in women.
Maria, Franekova, Erika, Halasova, Eva, Bukovska, Jan, Luptak, Dusan, Dobrota   +4 more
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Cytokine gene polymorphisms in psoriasis

British Journal of Dermatology, 2001
Cytokine production is under genetic control, and certain allelic variants of cytokine genes are associated with higher or lower cytokine production in vitro and in vivo. Psoriasis is associated with an overexpression in the involved skin of T-helper cell type 1 (Th1) cytokines, e.g.
Craven, N. M., Jackson, C. W., Kirby, B., Perrey, C., Pravica, V., Hutchinson, I. V., Griffiths, C. E M   +6 more
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Polymorphism of FCGR3A gene in sarcoidosis

Human Immunology, 2014
We showed increased level of immune complexes (ICs) with mycobacterial heat shock proteins (Mtb-hsp) and increased expression of receptors for Fc fragment of immunoglobulin G (FcγR) I-III on blood monocytes with their increased phagocytic activity, responsible for clearance of these ICs in sarcoidosis (SA).
Marlena J. Typiak, Krzysztof Rębała, Maria Dudziak, Anna Dubaniewicz   +3 more
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The elucidation of KIR2DL4 gene polymorphism

Molecular Immunology, 2008
The killer cell immunoglobulin-like receptors (KIRs) on NK cells recognize defined groups of HLA class I alleles. By this mechanism the NK cells fulfil a significant role in the first line of defense against infectious agents and cancer. For the treatment of leukaemia this NK cell allorecognition is of great importance.
Jennifer, Schellekens, Marcel G J, Tilanus, Erik H, Rozemuller   +2 more
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The polymorphism of the complement genes in HLA

Annales de l'Institut Pasteur / Immunologie, 1985
Genes coding for the complement proteins C2, C4A, C4B and factor B lie between HLA-D and HLA-B in HLA, the major histocompatibility complex in man. All the complement components are polymorphic, particularly C4, which has many alleles at each locus. The genetic complexity of C4 extends to the number of loci each of which may be deleted or duplicated on
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