Results 1 to 10 of about 3,013,569 (257)

The association between FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a among chronic granulocytic leukemia patients treated with imatinib mesylate [version 3; peer review: 2 approved]

F1000Research, 2022
Background: The gene FOXO3a has been elucidated to govern the development of chronic granulocytic leukemia (CGL). Moreover, it has been suggested that the levels of FOXO3a in circulation are affected by the FOXO3a rs4946936 gene polymorphism. However, no
Puji Rahayu, Yuyun Prabowowati Yueniwati, Jonny Karunia Fajar, Shinta Oktya Wardhani, Hani Susianti   +4 more
doaj   +1 more source

What is the Role of Mannose-Binding Lectin Gene Polymorphism in the Development of Acute Post-Streptococcal Glomerulonephritis?

Journal of Behçet Uz Children's Hospital, 2021
Objective: This study aims to determine the effects of the mannose-binding lectin (MBL) gene polymorphism on the clinical and laboratory findings, response to treatment, and progress of patients with acute post-streptococcal glomerulonephritis (APSGN ...
Deniz Güven, Mustafa Bak, Erkin Serdaroğlu, Ferda Özkınay, Ayça Aykut   +4 more
doaj   +1 more source

Is OPRM1 genotype a valuable predictor of VAS in patients undergoing laparoscopic radical resection of colorectal cancer with fentanyl?

BMC Anesthesiology, 2023
Objective This study was conducted to examine the association between the A118G polymorphism of the OPRM1 gene and the risk of increased VAS scores in patients with colorectal cancer who underwent laparoscopic radical resection for which fentanyl was ...
Yan Zhou, Lei Cao, Yihui Yang, Yaoyi Gao, Yihao Li, Beili Wang, Baishen Pan, Jian Huang, Wei Guo   +8 more
doaj   +1 more source

Frequency of occurrence of genetic polymorphisms associated with sports success in elite athletes in team sports

Спортивная медицина: наука и практика, 2021
Objective: to evaluate the frequency of occurrence of polymorphisms rs1815739 (ACTN3 gene), rs2016520 (PPARD gene), rs1042713 (ADRB2 gene), rs1799945 (HFE gene) in athletes of high­performance sports.Materials and methods: genotyping was performed using ...
E. Yu. Sorokina, N. N. Denisova, E. E. Keshabyants   +2 more
doaj   +1 more source

GENETIC POLYMORPHISM OF APE1 ASP148GLU IS NOT ASSOCIATED WITH BLADDER CANCER RISK IN A TURKISH POPULATION

Sabiad, 2023
Objective: The purpose of this investigative research was to investigatethe potential impact of a single nucleotide polymorphism (Asp148Glu) within the APE1 gene on the development of bladder cancer (BCa) andspread, and to investigate the interaction of ...
Taghi Ahmadi Rendi, Serhat Kılınç, Selçuk Erdem, Enes Değirmenci, Mehmet Öner Şanlı, Canan Küçükgergin, Semra Doğru Abbasoğlu   +6 more
doaj   +1 more source

Effect of Mannose-Binding Lectin Gene Polymorphism on Infection in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation

İstanbul Medical Journal, 2023
Introduction:The aim of this study was to investigate the association of mannose-binding lectin (MBL), which is involved in the classical complement pathway in innate immunity, with infections in the autologous hematopoietic stem cell transplantation ...
Aysun Halaçoğlu
doaj   +1 more source

The methylenetetrahydrofolate reductase genotype 677CT and non-alcoholic fatty liver disease have a synergistic effect on the increasing homocysteine levels in subjects from Chongqing, China

Genes and Diseases, 2019
The methylenetetrahydrofolate reductase (MTHFR) genotypes 677CT and 677TT are associated with elevated serum homocysteine (Hcy) levels by means of lowering the activity of MTHFR, and the increase in serum Hcy may be linked to increased susceptibility to ...
Xiaolin Wang, Yongli Zhou, Mingjun Zhang, Yonghong Wang, Bo Qin   +4 more
doaj   +1 more source

Relationship of genetic polymorphism of the acute phase marker of inflammation rs12218 of the SAA1 gene with clinical phenotypes of juvenile idiopathic arthritis

Современная ревматология, 2021
Objective: to test the hypothesis of a possible relationship between the rs12218 polymorphism of the SAA1 gene and a predisposition to different clinical phenotypes of juvenile idiopathic arthritis (JIA).Patients and methods.
M. Yu. Krylov, E. S. Fedorov, S. O. Salugina   +2 more
doaj   +1 more source

Vascular Endothelial Growth Factor and Interleukin 1-b Gene Polymorphisms as a Genetic Predictor for Uterine Leiomyoma [PDF]

Zagazig University Medical Journal
Background: The most frequent benign gynecological tumor in premenopausal women is leiomyoma, generally known as fibroids. Leiomyomas have a significant financial effect, impacting an estimated 11 million women.
Marwa Abdelghany, Haidy Zidan, Hala Mohamed Mowafy, Shereen ElShabrawy   +3 more
doaj   +1 more source

Розподіл алельних варіантів генів інгібіторів та активаторів ектопічної кальцифікації у пацієнтів із гострим коронарним синдромом

Фактори експериментальної еволюції організмів, 2017
Aim. The study of the distribution of polymorphic variants K121Q (gene ENPP1), T134967G (gene ANKH) and A69314G (gene TNAP) is in patients with acute coronary syndrome. Methods. Venous blood of 118 patients with ACS and 110 persons of control group were
V. Yu. Harbuzova, O. A. Obukhova, I. O. Rozumenko, Ye. I. Dubovyk, T. M. Oleshko, Ye. A. Harbuzova, D. V. Shvachko, O. V. Ataman   +7 more
doaj   +1 more source