Results 1 to 10 of about 420,360 (120)

Identification of gene candidates associated with Irritable bowel syndrome [PDF]

Scripta Medica, 2022
Background/Aim: Irritable bowel syndrome (IBS) belongs to the gastrointestinal disorders characterised by abdominal discomfort and pain, altered constipation, diarrhoea and stomach distension.
Milovac Irina, Vidović Vanja, Ramić Jasmin, Lojo-Kadrić Naida, Hadžić Maida, Mavija Zoran, Vidović Stojko, Pojskić Lejla   +7 more
doaj   +1 more source

Association of CNR1 and INSIG2 polymorphisms with antipsychotics-induced weight gain: a prospective nested case–control study

Scientific Reports, 2021
Weight gain is a frequent and severe adverse reaction in patients taking antipsychotics. The objective was to further investigate in a natural setting influential risk factors associated with clinically significant weight gain. An observational follow-up
Natalia Jimeno, Veronica Velasco-Gonzalez, Inmaculada Fierro, Mercedes Duran, Alfonso Carvajal   +4 more
doaj   +1 more source

Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis

Archives of Medical Science, 2021
Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of unknown etiology which causes progressive deterioration of the joints, leading to severe pain and functional disability.
Noelia Marquez Pete, Cristina Perez Ramirez, Maria del Mar Maldonado Montoro, Fernando Martinez Martinez, Fernando Fernández-Llimos, Antonio Sánchez Pozo, María del Carmen Ramirez Tortosa, Alberto Jiménez Morales   +7 more
doaj   +1 more source

Differential Effect of Polymorphisms on Body Mass Index Across the Life Course of Japanese: The Japan Multi-Institutional Collaborative Cohort Study

Journal of Epidemiology, 2021
Background: Obesity is a reported risk factor for various health problems. Genome-wide association studies (GWASs) have identified numerous independent loci associated with body mass index (BMI). However, most of these have been focused on Europeans, and
Madoka Iwase, Keitaro Matsuo, Masahiro Nakatochi, Isao Oze, Hidemi Ito, Yuriko Koyanagi, Tomotaka Ugai, Yumiko Kasugai, Asahi Hishida, Kenji Takeuchi, Rieko Okada, Yoko Kubo, Chisato Shimanoe, Keitaro Tanaka, Hiroaki Ikezaki, Masayuki Murata, Toshiro Takezaki, Daisaku Nishimoto, Nagato Kuriyama, Etsuko Ozaki, Sadao Suzuki, Miki Watanabe, Haruo Mikami, Yohko Nakamura, Hirokazu Uemura, Sakurako Katsuura-Kamano, Kiyonori Kuriki, Yoshikuni Kita, Naoyuki Takashima, Masato Nagino, Yukihide Momozawa, Michiaki Kubo, Kenji Wakai   +32 more
doaj   +1 more source

HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults

Frontiers in Immunology, 2023
Autoimmune hepatitis (AIH) is a chronic and progressive disease of the liver. This is a multifactorial autoimmune disease with both environmental factors and genetic factors playing a role in its pathogenesis.
Nishtha Ahuja, Jagdeep Singh, Ranjana Walker Minz, Shashi Anand, Ashim Das, Sunil Taneja   +5 more
doaj   +1 more source

FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls—The GEA Mexican Study

Biomolecules, 2022
FOXA3 is a transcription factor involved in the macrophage cholesterol efflux and macrophage reverse cholesterol transport reducing the atherosclerotic lesions.
Gilberto Vargas-Alarcón, José Manuel Fragoso, Julian Ramírez-Bello, Rosalinda Posadas-Sánchez   +3 more
doaj   +1 more source

Genome-Wide Identification and Development of LTR Retrotransposon-Based Molecular Markers for the Melilotus Genus

Plants, 2021
Melilotus is an important genus of legumes with industrial and medicinal value, partly due to the production of coumarin. To explore the genetic diversity and population structure of Melilotus, 40 accessions were analyzed using long terminal repeat (LTR)
Zifeng Ouyang, Yimeng Wang, Tiantian Ma, Gisele Kanzana, Fan Wu, Jiyu Zhang   +5 more
doaj   +1 more source

Genetic Variations Associated with Sleep Disorders in Patients with Schizophrenia: A Systematic Review

Medicines, 2018
Background: Schizophrenic patients commonly suffer from sleep disorders which are associated with acute disease severity, worsening prognoses and a poorer quality of life.
Konstantinos Assimakopoulos, Katerina Karaivazoglou, Maria Skokou, Marina Kalogeropoulou, Panagiotis Kolios, Philippos Gourzis, George P. Patrinos, Evangelia Eirini Tsermpini   +7 more
doaj   +1 more source

Cytokine Gene Polymorphisms in Chinese Children with Idiopathic Nephrotic Syndrome [PDF]

Iranian Journal of Immunology, 2022
Background: Cytokines play a role in the progression of idiopathic-nephrotic syndrome (INS). Objectives: To investigate the association of different cytokine genes polymorphisms with INS incidence and response to steroid therapy in Chinese children ...
Wei Li, Lin Li, Lin He, Yun Du, Hai-Dong Fu, Zhao-Yang Peng, Wen-Qing Xiang, Jian-Hua Mao   +7 more
doaj   +1 more source

Polymorphisms in Th1/Th2 cytokine Genes, hormone replacement therapy, and risk of non-Hodgkin lymphoma

Frontiers in Oncology, 2011
We conducted a population-based case-control study in Connecticut women to test the hypothesis that genetic variations in Th1 and Th2 cytokine genes modify the relationship between hormone replacement therapy (HRT) and risk of non-Hodgkin lymphoma (NHL).
Gongjian eZhu, Gongjian eZhu, Dongsheng ePan, Dongsheng ePan, Tongzhang eZheng, Qing eLan, Xuezhong eChen, Xuezhong eChen, Yingtai eChen, Yingtai eChen, Christopher eKim, Xiaofeng eBi, Xiaofeng eBi, Theodore eHolford, Peter eBoyle, Brian eLeaderer, Stephen eChanock, Nathaniel eRothman, Yawei eZhang   +18 more
doaj   +1 more source