Results 11 to 20 of about 249,399 (261)

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]

, 2004
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Kabesch, Michael, Stachel, Daniel, Carr, David, Schmid, Irene, Woitsch, Bernd, Weiland, Stephan K., Fritzsch, Christian, Mutius, Erika von   +7 more
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Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]

, 2014
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Sibley, CH, Malmberg, M, Nsobya, SL, Lebras, J, Nsanzabana, C, Faucher, JF, Thwing, J, Somé, AF, Ogutu, B, Houzé, S, Gadalla, NB, Björkman, A, Desai, M, Schramm, B, Venkatesan, M, Oguike, M, Ménard, D, Hamour, S, Plowe, CV, Dhorda, M, Djimdé, AA, Borrmann, S, Dorsey, G, Wong, RP, Fröberg, G, Stepniewska, K, Guérin, P, Kiechel, JR, Baliraine, FN, Johnson, J, Rombo, L, Kariuki, S, Ouédraogo, JB, Ademowo, G, Kofoed, PE, Grivoyannis, A, Falade, C, Sutherland, CJ, Nzila, A, Piola, P, Zongo, I, Eshetu, T, Dahal, P, Kamugisha, E, Ngasala, B, El-Sayed, BB, Rosenthal, PJ, Nosten, F, Eyase, F, Ursing, J, Otienoburu, SD, Davis, TM, Adam, I, Kironde, F, Zeynudin, A, Checchi, F, Moriera, C, Arze, C, Berens-Riha, N, Mwai, L, Price, RN, Faucher, Jean-François, Houzé, Sandrine, Somé, A Fabrice, Sutherland, Colin, Checchi, Francesco, Berens-Riha, Nicole, Davis, Timothy ME, Björkman, Anders, Asaq Molecular Marker Study Group, Rosenthal, Philip, Eyase, Frederick, Kariuki, Simon, Mårtensson, Andreas,, Davis, Timothy, Gadalla, Nahla B, Ménard, Didier, Arze, Cesar, Djimdé, Abdoulaye A, Fröberg, Gabrielle, Ursing, Johan, Desai, Meghna, Mårtensson, Andreas, Ouédraogo, Jean-Bosco, Mwai, Leah, Kironde, Fred, Djimde, Abdoulaye, Dorsey, Grant, Johnson, Jacob, Guérin, Philippe, Somé, A. Fabrice, Oguike, Alexis Nzila Mary, LeBras, Poul-Erik Kofoed Jacques, Kofoed, Poul-Erik, Dahal, Prabin, Nzila, Alexis, Wong, Rina PM, Nsobya, Samuel L, Zongo, Issaka, Gadalla, Nahla, Dhorda, Meghna Desai Mehul, Plowe, Christopher,, Rombo, Lars,, Stepniewska, Kasia, Adam, Ishag, Price, Ric N, Rombo, Lars, Kamugisha, Erasmus, Piola, Patrice, El-Sayed, Badria, Plowe, Christopher, V, Sutherland, Colin J, Otienoburu, Sabina Dahlström, Grivoyannis, Anastasia, Malmberg, Maja, Hamour, Sally, Ogutu, Bernhards, Wong, Rina, Sibley, Carol Hopkins, Ngasala, Billy, Oguike, Mary, Venkatesan, Meera, Baliraine, Frederick N, LeBras, Jacques, El-Sayed, Badria B, Thwing, Julie, Price, Ric, Moriera, Clarissa, Kiechel, Jean-René, Nsanzabana, Christian, Rosenthal, Philip J, Ademowo, George, Falade, Catherine, Schramm, Birgit, Wong, Rina P M, Plowe, Christopher V, Eshetu, Teferi, Davis, Timothy M E, Dhorda, Mehul, Borrmann, Steffen, Nosten, Francois, Baliraine, Frederick, Zeynudin, Ahmed, Nsobya, Samuel, Martensson, A   +144 more
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Genome-Wide Identification and Development of LTR Retrotransposon-Based Molecular Markers for the Melilotus Genus

Plants, 2021
Melilotus is an important genus of legumes with industrial and medicinal value, partly due to the production of coumarin. To explore the genetic diversity and population structure of Melilotus, 40 accessions were analyzed using long terminal repeat (LTR)
Zifeng Ouyang, Yimeng Wang, Tiantian Ma, Gisele Kanzana, Fan Wu, Jiyu Zhang   +5 more
doaj   +1 more source

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development [PDF]

, 2016
Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never been addressed whether SNPs in CHI3L1 and cord blood YKL-40 levels
Gorlanova, Olga, Olga Gorlanova, Latzin, Philipp, Frey, Urs, Jakob Usemann, Urs Frey, Philipp Latzin, Dominik Hartl, Mack, Ines, Hartl, Dominik, Schmidt, Anne, Röösli, Martin, Ines Mack, Usemann, Jakob, Martin Röösli, Anne Schmidt, Latzin P, Usemann J, Schmidt A, Röösli M, Mack I, Hartl D, Gorlanova O, Frey U   +23 more
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Genetic Variations Associated with Sleep Disorders in Patients with Schizophrenia: A Systematic Review

Medicines, 2018
Background: Schizophrenic patients commonly suffer from sleep disorders which are associated with acute disease severity, worsening prognoses and a poorer quality of life.
Konstantinos Assimakopoulos, Katerina Karaivazoglou, Maria Skokou, Marina Kalogeropoulou, Panagiotis Kolios, Philippos Gourzis, George P. Patrinos, Evangelia Eirini Tsermpini   +7 more
doaj   +1 more source

Cytokine Gene Polymorphisms in Chinese Children with Idiopathic Nephrotic Syndrome [PDF]

Iranian Journal of Immunology, 2022
Background: Cytokines play a role in the progression of idiopathic-nephrotic syndrome (INS). Objectives: To investigate the association of different cytokine genes polymorphisms with INS incidence and response to steroid therapy in Chinese children ...
Wei Li, Lin Li, Lin He, Yun Du, Hai-Dong Fu, Zhao-Yang Peng, Wen-Qing Xiang, Jian-Hua Mao   +7 more
doaj   +1 more source

Polymorphisms in Th1/Th2 cytokine Genes, hormone replacement therapy, and risk of non-Hodgkin lymphoma

Frontiers in Oncology, 2011
We conducted a population-based case-control study in Connecticut women to test the hypothesis that genetic variations in Th1 and Th2 cytokine genes modify the relationship between hormone replacement therapy (HRT) and risk of non-Hodgkin lymphoma (NHL).
Gongjian eZhu, Gongjian eZhu, Dongsheng ePan, Dongsheng ePan, Tongzhang eZheng, Qing eLan, Xuezhong eChen, Xuezhong eChen, Yingtai eChen, Yingtai eChen, Christopher eKim, Xiaofeng eBi, Xiaofeng eBi, Theodore eHolford, Peter eBoyle, Brian eLeaderer, Stephen eChanock, Nathaniel eRothman, Yawei eZhang   +18 more
doaj   +1 more source

Meta-Analysis of Vitamin D Receptor Gene Polymorphisms in Childhood Asthma

Frontiers in Pediatrics, 2022
We conducted the systematic review to investigate the potential relationship between the vitamin polymorphisms of D receptor (VDR) gene and childhood asthma.
Yong Zhou, Sheng Li
doaj   +1 more source

A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme [PDF]

, 2012
Background: Low muscle mass and function have been associated with poorer indicators of physical capability in olderpeople, which are in-turn associated with increased mortality rates.
Kumari, Meena, Hardy, R, John M. Starr (107707), Cooper, R, Gunnell, David, Rachel Cooper, Alfred Tamuno, Alfred, T, Kuh, D., Kumari Meena, Yoav Ben-Shlomo, Tom R Gaunt, Meena Kumari (95278), Kumari, M, Gaunt, Tom R., Cooper Cyrus, Martin, RM, Hardy, R., Team, HS, Sayer Avan Aihie, John M Starr, Day, I.N.M., Ben-Shlomo, Yoav, Ian J. Deary (107724), Tamuno Alfred, Harris, Sarah E, Sayer, AA, Sarah E Harris, Ian N M Day, Ian J Deary, HALCyon Study Team, The HALCyon study team, Gaunt Tom R., Richard M. Martin (176602), Kuh, Diana, Rebecca Hardy (188906), Deary, Ian J, Day, Ian N. M., Martin Richard M., Alfred, Tamuno, Richard M Martin, Yoav Ben-Shlomo (95286), Cooper, C., Diana Kuh, Ben-Shlomo, Y., Starr John M., Deary Ian J., Cooper, C, Martin, R.M., Starr, J.M., Rachel Cooper (188902), David Gunnell, Gaunt, TR, David Gunnell (41947), Harris Sarah E., Kuh Diana, Kumari, M., Gunnell, D, Craig, Leone, Gunnell David, Starr, John M., Starr, John M, Meena Kumari, Ben-Shlomo, Y, Cyrus Cooper (141250), Cooper, R., Martin, Richard M, Sayer, A.A., Cyrus Cooper, Harris, S.E., Hardy, Rebecca, Starr, JM, Harris, SE, ?, ?, Alfred, T., Avan Aihie Sayer, Cooper, Rachel, Deary, IJ, Gunnell, D., Cooper Rachel, Ian N. M. Day (95288), Avan Aihie Sayer (188916), Rebecca Hardy, Hardy Rebecca, Deary, Ian J., Martin, Richard M., Harris, Sarah E., Day Ian N. M., Cooper, Cyrus, Day, INM, Sayer, Avan Aihie, Tom R. Gaunt (95274), Day, Ian N M, Gaunt, Tom R, Tamuno Alfred (188897), Kuh, D, Gaunt, T.R., Ben-Shlomo Yoav, Sarah E. Harris (107676), Diana Kuh (188923)   +99 more
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Absence of Association between CCR5 rs333 Polymorphism and Childhood Acute Lymphoblastic Leukemia

Advances in Hematology, 2014
Acute lymphoblastic leukemia (ALL) is a malignant disorder that originates from one single hematopoietic precursor committed to B- or T-cell lineage. Ordinarily, these cells express CCR5 chemokine receptor, which directs the immune response to a cellular
Carlos Eduardo Coral de Oliveira, Marla Karine Amarante, Aparecida de Lourdes Perim, Patricia Midori Murobushi Ozawa, Carlos Hiroki, Glauco Akelinghton Freire Vitiello, Roberta Losi Guembarovski, Maria Angelica Ehara Watanabe   +7 more
doaj   +1 more source