Results 31 to 40 of about 249,399 (261)
Frontiers in Genetics, 2012 Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases.
Angela Margarita Roco +15 more
doaj +1 more source
Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population
Molecular Genetics & Genomic Medicine, 2021 Background Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes about 3.0% of therapeutic drugs. Drugs metabolized mainly by CYP2B6 include artemisinin, bupropion, cyclophosphamide, efavirenz, ketamine, and methadone.
Sagheer Ahmed +4 more
doaj +1 more source
, 2017 polymorphism for coverage >8. Includes all bcf files and a Excel file with summaries and comparisons with polymorphisms from other species. To assess vcf files with polymorphisms with coverage >20 (after reads2snp), please contact the corresponding ...
Pierce, N. Tessa +9 more
core +1 more source
Advanced Biomedical Research, 2016 Background: Variations in the hepatic lipase (HL) gene are the potential candidate for coronary artery disease (CAD) especially in type 2 diabetes mellitus (T2DM) in diverse populations. We assessed the association of -514C/T and -250G/A polymorphisms in
Ghorban Mohammadzadeh +3 more
doaj +1 more source
Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population. [PDF]
, 2012 The Brazilian Amazon is a hypo-endemic malaria region with nearly 300,000 cases each year. A variety of genetic polymorphisms, particularly in erythrocyte receptors and immune response related genes, have been described to be associated with ...
Rockett, Kirk A. +31 more
core +1 more source
Interleukin-1[Alpha] production in periodontal disease: the interaction of bacteria and gene polymorphisms. [PDF]
, 2007 PhDThere is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host response to bacteria and the tissue destruction associated with periodontal disease.
Bostanci, Nagihan
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Paraoxonase Gene Polymorphisms and Aortic Calcification
International Journal of Gerontology, 2010 Background: Aortic arch calcification is correlated with the extent of atherosclerosis and is a predictor of future cardiovascular risk. The paraoxonase (PON) gene can reduce the risk of atherosclerosis development.
Jinzi Wu +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CX3CR1 Polymorphisms are associated with atopy but not asthma in German children [PDF]
, 2007 Chemokines and their receptors are involved in many aspects of immunity. Chemokine CX3CL1, acting via its receptor CX3CR1, regulates monocyte migration and macrophage differentiation as well as T cell-dependent inflammation.
Depner, Martin +17 more
core +1 more source