Whole genome sequencing-based mapping and candidate identification of mutations from fixed zebrafish tissue [PDF]
As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology or through transgenic approaches, such as many nervous system defects, has also increased.
Ackerman, Sarah D +8 more
core +3 more sources
Parts & Pools: a framework for modular design of synthetic gene circuits
Published in 2008, Parts & Pools represents one of the □first attempts to conceptualizethe modular design of bacterial synthetic gene circuits with Standard Biological Parts (DNAsegments) and Pools of molecules referred to as common signal carriers (e.g.
Mario Andrea Marchisio
doaj +1 more source
Spd2 assists Spd1 in modulation of RNR architecture but does not regulate deoxynucleotide pools [PDF]
In yeasts, small intrinsically disordered proteins (IDPs) modulate ribonucleotide reductase (RNR) activity to ensure an optimal supply of dNTPs for DNA synthesis. The S. pombe Spd1 protein can directly inhibit the large RNR subunit (R1), import the small
Basrai +37 more
core +1 more source
Reduction of dynamical biochemical reaction networks in computational biology [PDF]
Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression.
Gorban, Alexander N. +3 more
core +6 more sources
Matching population diversity of rhizobial nodA and legume NFR5 genes in plant–microbe symbiosis
We hypothesized that population diversities of partners in nitrogen‐fixing rhizobium–legume symbiosis can be matched for “interplaying” genes. We tested this hypothesis using data on nucleotide polymorphism of symbiotic genes encoding two components of ...
Anna A. Igolkina +4 more
doaj +1 more source
A Hot Spot of Olive Biodiversity in the Tunisian Oasis of Degache
Tunisia is one of the world’s largest producers of olive oil, and it preserves pools of olive genetic diversity that are still unexplored. A recent prospection and collection program of the National Gene Bank of Tunisia (NGBT) focused on the vast oasis ...
Olfa Saddoud Deddabi +10 more
doaj +1 more source
Bayesian estimation of diagnostic accuracy of fecal culture and PCR-based tests for the detection of Salmonella enterica in California cull dairy cattle. [PDF]
Epidemiological studies of low prevalence disease problems are often hindered by the high cost of diagnostic testing. The objective of this study was to evaluate PCR screening of both individual and pooled fecal samples from culled dairy cows for the ...
Adaska, John M +8 more
core +1 more source
Microbial communities and arsenic biogeochemistry at the outflow of an alkaline sulfide-rich hot spring. [PDF]
Alkaline sulfide-rich hot springs provide a unique environment for microbial community and arsenic (As) biogeochemistry. In this study, a representative alkaline sulfide-rich hot spring, Zimeiquan in the Tengchong geothermal area, was chosen to study ...
Dai, Xinyue +9 more
core +1 more source
Genetic enhancement for grain yield in chickpea – accomplishments and resetting research agenda [PDF]
Chickpea (Cicer arietinum L.), commonly known as ‘gram’ is one of the major pulse crops of India covering 7.97 m ha areaproducing 7.06 m t of the grains and registering all time productivity of 885 kg/ha during 2008-09.
S.K. Chaturvedi and N. Nadarajan
doaj
The hyperdominant tropical tree Eschweilera coriacea (Lecythidaceae) shows higher genetic heterogeneity than sympatric Eschweilera species in French Guiana [PDF]
Background and aims – The evolutionary history of Amazonia’s hyperabundant tropical tree species, also known as “hyperdominant” species, remains poorly investigated. We assessed whether the hyperdominant Eschweilera coriacea (DC.) S.A.Mori (Lecythidaceae)
Myriam Heuertz +12 more
doaj +3 more sources

