Results 131 to 140 of about 4,645 (244)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

DASS-21 Stress, but Not Anxiety or Depression, Is Associated with Premenstrual Stress. [PDF]

J Clin Med
Turner JV, Alefsen Y, McLindon LA, Turner DV, Ecochard R.   +4 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Genome-wide association study of seedling leaf rust resistance in European winter wheat cultivars. [PDF]

J Appl Genet
Czembor PC, Piechota U, Song J, Mańkowski D, Radecka-Janusik M, Piaskowska D, Słowacki P, Kilian A.   +7 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Plant Functional Traits or Microbiomes Associated with Diseases, Pests, Human Activities and Climate Change. [PDF]

Plants (Basel)
Guo JW, Yang H, Wang X.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Interplay between genes and social environment: from epigenetics to precision medicine. [PDF]

Cell Death Discov
Caporali S, Russo S, Leist M, Wirtz PH, Amelio I.   +4 more
europepmc   +1 more source

Virulence and genetic analysis of <i>Puccinia graminis tritici</i> in the Indian sub-continent from 2016 to 2022 and evaluation of wheat varieties for stem rust resistance. [PDF]

Front Plant Sci, 2023
Prasad P, Thakur R, Bhardwaj SC, Savadi S, Gangwar OP, Lata C, Adhikari S, Kumar S, Kundu S, Manjul AS, Prakasha TL, Navathe S, Hegde GM, Game BC, Mishra KK, Khan H, Gupta V, Mishra CN, Kumar S, Kumar S, Singh G.   +20 more
europepmc   +1 more source

IDENTIFICATION OF PHYSIOLOGIC RACES OF Puccinia triticina AND POSTULATED GENES OF RESISTANCE IN CERTAIN EGYPTIAN COMMERCIAL WHEAT CULTIVARS [PDF]

Journal of Plant Protection and Pathology, 2010
I. Youssef, Doaa El-Naggar, Gamalat Hermas, S. Negm   +3 more
openaire   +1 more source