Results 151 to 160 of about 2,702,537 (246)

A novel human <i>Streptomyces</i> strain redresses malignancy by inducing apoptosis and regaining gut homeostasis. [PDF]

mSystems
Wang Y-H, Yuan B-J, Meng Y, Xu H-T, Gao X-Y, Liu L, Tian H-D, Wang X, Zhang X-H, Zhu S-L, Johnston RN, Tang L, Liu G-R, Liu S-L.   +13 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Run for your sons: paternal exercise boosts offspring fitness. [PDF]

Trends Endocrinol Metab
Schneider AE, Conine CC.
europepmc   +1 more source

Envelope for Miss Gene E. Smith, Beaver Dam, Wisconsin, July 24, 1865

An item in the George Woodard and Gene Smith letters ...
Smith, Gene E.
core  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Reaction of Wheat to European Virulence Races of Common Bunt (<i>Tilletia</i> spp.) and Mapping Race-Specific Resistance Genes Using SNP Markers. [PDF]

Plants (Basel)
Borgen A, Christensen DK.
europepmc   +1 more source

Envelope for Miss Gene E. Smith, Beaver Dam, Wisconsin, July, ca. 1865

An item in the George Woodard and Gene Smith letters ...
Smith, Gene E.
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

DASS-21 Stress, but Not Anxiety or Depression, Is Associated with Premenstrual Stress. [PDF]

J Clin Med
Turner JV, Alefsen Y, McLindon LA, Turner DV, Ecochard R.   +4 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source