Results 211 to 220 of about 563,010 (309)

Enhancing Molecular Network-Based Cancer Driver Gene Prediction Using Machine Learning Approaches: Current Challenges and Opportunities. [PDF]

J Cell Mol Med
Zhang H, Lin C, Chen Y, Shen X, Wang R, Chen Y, Lyu J.   +6 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Modeling Between-Study Heterogeneity for Improved Reproducibility in Gene Signature Selection and Clinical Prediction [PDF]

, 2017
Naim U. Rashid, Quefeng Li, Jen Jen Yeh, Joseph G. Ibrahim   +3 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

BenchAMRking: a Galaxy-based platform for illustrating the major issues associated with current antimicrobial resistance (AMR) gene prediction workflows. [PDF]

BMC Genomics
Strepis N, Dollee D, Vrins D, Vanneste K, Bogaerts B, Carrillo C, Bharat A, Horan K, Sherry NL, Seemann T, Howden BP, Hiltemann S, Chindelevitch L, Stubbs AP, Hays JP.   +14 more
europepmc   +1 more source

<p>Digital Immune-Related Gene Expression Signatures In High-Grade Serous Ovarian Carcinoma: Developing Prediction Models For Platinum Response</p>

, 2019
Fabian Mairinger, Ágnes Bánkfalvi, Kurt Werner Schmid, Elena Mairinger, Paweł Mach, Robert Walter, Sabrina Borchert, Sabine Kasimir‐Bauer, Rainer Kimmig, Paul Buderath   +9 more
openalex   +2 more sources

A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients [PDF]

, 2010
Stéphanie Roessler, Hu-Liang Jia, Anuradha Budhu, Marshonna Forgues, Qing-Hai Ye, Ju‐Seog Lee, Snorri S. Thorgeirsson, Zhongtang Sun, Zhao-You Tang, Lun‐Xiu Qin, Xin Wei Wang   +10 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ensemble decision of local similarity indices on the biological network for disease related gene prediction. [PDF]

PeerJ
Cingiz MÖ.
europepmc   +1 more source

Prediction of dyslipidemia using gene mutations, family history of diseases and anthropometric indicators in children and adolescents: The CASPIAN-III study

, 2018
Hamid Reza Marateb, Mohammad Reza Mohebian, Shaghayegh Haghjooy Javanmard, Amir Ali Tavallaei, Mohamadhasan Tajadini, Motahar Heidari‐Beni, Miguel Ángel Mañanas, Mohammad Esmaeil Motlagh, Ramin Heshmat, Marjan Mansourian, Roya Kelishadi   +10 more
openalex   +1 more source