Disease-gene prediction based on preserving structure network embedding. [PDF]
Ma J, Qin T, Xiang J.
europepmc +1 more source
GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions [PDF]
J Besemer
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Integrated de novo gene prediction and peptide assembly of metagenomic sequencing data. [PDF]
Thippabhotla S+6 more
europepmc +1 more source
MRP8, A New Member of ABC Transporter Superfamily, Identified by EST Database Mining and Gene Prediction Program, Is Highly Expressed in Breast Cancer [PDF]
Tapan K. Bera+4 more
openalex +1 more source
Gene modeling and prediction v1
We performed a considerate prediction of intact protein-coding gene models using three independent approaches, i.e.,de novoprediction, homology-based method, and RNA-Seq approach.
openaire +2 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC. [PDF]
Chi H+14 more
europepmc +1 more source
GeneMachine: gene prediction and sequence annotation [PDF]
Izabela Makałowska+2 more
openalex +1 more source