Results 261 to 270 of about 9,720,197 (382)

Bias in resistance gene prediction due to repeat masking

Nature Plants, 2018
P. Bayer, D. Edwards, J. Batley
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Enhancing Molecular Network-Based Cancer Driver Gene Prediction Using Machine Learning Approaches: Current Challenges and Opportunities. [PDF]

J Cell Mol Med
Zhang H, Lin C, Chen Y, Shen X, Wang R, Chen Y, Lyu J.   +6 more
europepmc   +1 more source

ResCap: plant resistance gene prediction and probe generation pipeline for resistance gene sequence capture. [PDF]

Bioinform Adv, 2021
Kushwaha SK, Åhman I, Bengtsson T.
europepmc   +1 more source

Digital filters for gene prediction applications [PDF]

, 2002
P. P. Vaidyanathan, Byung-Jun Yoon
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

BenchAMRking: a Galaxy-based platform for illustrating the major issues associated with current antimicrobial resistance (AMR) gene prediction workflows. [PDF]

BMC Genomics
Strepis N, Dollee D, Vrins D, Vanneste K, Bogaerts B, Carrillo C, Bharat A, Horan K, Sherry NL, Seemann T, Howden BP, Hiltemann S, Chindelevitch L, Stubbs AP, Hays JP.   +14 more
europepmc   +1 more source

Ancestry may confound genetic machine learning: Candidate-gene prediction of opioid use disorder as an example. [PDF]

Drug Alcohol Depend, 2021
Hatoum AS, Wendt FR, Galimberti M, Polimanti R, Neale B, Kranzler HR, Gelernter J, Edenberg HJ, Agrawal A.   +8 more
europepmc   +1 more source

A Bayesian framework for combining gene predictions [PDF]

, 2002
Vladimir Pavlović, Ashutosh Garg, Simon Kasif   +2 more
openalex   +1 more source