Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study. [PDF]
Zhong Y +5 more
europepmc +1 more source
Analysis of therdxAgene in high-level metronidazole-resistant clinical isolates confirms a limited use ofrdxAmutations as a marker for prediction of metronidazole resistance inHelicobacter pylori [PDF]
Stefan Bereswill +4 more
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Correction: Exploring crop genomes: assembly features, gene prediction accuracy, and implications for proteomics studies. [PDF]
Abbas Q +4 more
europepmc +1 more source
Exegesis: a procedure to improve gene predictions and its use to find immunoglobulin superfamily proteins in the human and mouse genomes [PDF]
Bernard de Bono
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Hayai-Annotation: A functional gene prediction tool that integrates orthologs and gene ontology for network analysis in plant species. [PDF]
Ghelfi A, Isobe S.
europepmc +1 more source
Algorithm for Finding Optimal Gene Sets in Microarray Prediction
J. M. Deutsch
openalex +2 more sources
Outcome of clinical versus genetic family screening in hypertrophic cardiomyopathy with focus on cardiac beta-myosin gene mutations Prediction of clinical status—is molecular genetics a new tool for the management of hypertrophic cardiomyopathy in clinical practice? [PDF]
Christian Hengstenberg
openalex +1 more source

