Results 131 to 140 of about 6,798,395 (302)

Establishment of a novel human lymphoblastic cell strain with the long arm of chromosome 11 aberration without MLL rearrangement

Scientific Reports, 2017
At present, all cell strains derived from acute lymphoblastic leukemia (ALL) patients with the long arm of chromosome 11 aberration are accompanied with mixed lineage leukemia (MLL) gene rearrangement.
Qian Wang, Lin Zhuang, Pei Li, Qiang Niu, Ping Zhu, Miao-Xia He, Hui Jiang, Chang-Cheng Liu, Min-Jun Wang, Li Chen, Hui Cheng, Yan Ma, Xiao-Xia Hu, Yi-Ping Hu, Xiao-Ping Xu   +14 more
doaj   +1 more source

Heterogeneous rates of genome rearrangement contributed to the disparity of species richness in Ascomycota

BMC Genomics, 2018
Background Chromosomal rearrangements have been shown to facilitate speciation through creating a barrier of gene flow. However, it is not known whether heterogeneous rates of chromosomal rearrangement at the genome scale contributed to the huge ...
Ahmad Rajeh, Jie Lv, Zhenguo Lin
doaj   +1 more source

THE USE OF DUPLICATION-GENERATING REARRANGEMENTS FOR STUDYING HETEROKARYON INCOMPATIBILITY GENES IN NEUROSPORA [PDF]

, 1975
David D. Perkins
openalex   +1 more source

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling

Journal of Experimental Medicine, 2005
To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene rearrangements by quantitative PCR analysis in nine consecutive T cell developmental stages, including ...
W. Dik, K. Pike-Overzet, F. Weerkamp, D. de Ridder, E. D. de Haas, M. Baert, P. J. van der Spek, E. Koster, M. Reinders, J. V. van Dongen, A. Langerak, F. Staal   +11 more
semanticscholar   +1 more source

Acute leukemias associated with the 4;11 chromosome translocation have rearranged immunoglobulin heavy chain genes [PDF]

, 1985
WM Crist, ML Cleary, Grossi Ce, EF Prasthofer, GD Heggie, G A Omura, AJ Carroll, MP Link, Jeffrey Sklar   +8 more
openalex   +1 more source

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice [PDF]

, 1994
We have examined the regulatory role of the individual components of the immunoglobulin antigen receptor in B-cell development by transgenic complementation of Rag-1 deficient (Rag-1⁻) mice. Complementation with a membrane µ heavy chain (µHC) gene allows
Baltimore, David, Corcoran, Lynn M., Hardy, Richard R., Nemazee, David, Nussenzweig, Michel C., Roman, Christopher A. J., Schlissel, Mark S., Shinton, Susan A., Silver, Daniel P., Spanopoulou, Eugenia   +9 more
core  

Quantifying evolutionary constraints on B cell affinity maturation

, 2014
The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through high-throughput ...
Bedford, Trevor, Bradley, Philip, Matsen IV, Frederick A., McCoy, Connor O., Minin, Vladimir N., Robins, Harlan   +5 more
core   +2 more sources

Variações do Problema de Distância de Rearranjos [PDF]

arXiv
Considering a pair of genomes, the goal of rearrangement distance problems is to estimate how distant these genomes are from each other based on genome rearrangements. Seminal works in genome rearrangements assumed that both genomes being compared have the same set of genes (balanced genomes) and, furthermore, only the relative order of genes and their
arxiv  

Cross-lineage gene rearrangements in human leukemic B-precursor cells occur frequently with V-DJ rearrangements of IgH genes [PDF]

, 1989
Tetsuya Nosaka, K Kita, H Miwa, Keiki Kawakami, Toshio Ikeda, Toshiyuki Ohno, Norihiro Matsuoka, Yuu Arita, S Doi, M Nishikori   +9 more
openalex   +1 more source

Long-term cultures of murine fetal liver retain very early B lymphoid phenotype. [PDF]

, 1984
Long-term cultures of murine fetal liver have been successfully established using a modification of our in vitro bone marrow culture system (14, 15).
Denis, KA, St Claire, JI, Treiman, LJ, Witte, ON   +3 more
core