Results 141 to 150 of about 150,131 (316)

Clonal CCND1 Gene Rearrangement [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

EGFR Gene Rearrangement [PDF]

, 2020
openaire   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Positive Selection Drives Mitochondrial Gene Rearrangement in Sternorrhyncha (Insecta: Hemiptera). [PDF]

Ecol Evol
Zhao TY, Wei JF, Li CF, Chen YN, Lü L, Wang F.   +5 more
europepmc   +1 more source

Updates in KMT2A Gene Rearrangement in Pediatric Acute Lymphoblastic Leukemia. [PDF]

Biomedicines, 2023
Górecki M, Kozioł I, Kopystecka A, Budzyńska J, Zawitkowska J, Lejman M.   +5 more
europepmc   +1 more source

NUP98 Gene Rearrangement [PDF]

, 2020
openaire   +1 more source

Prevalence and Clinical Outcomes for Patients With ALK Gene Rearrangement in Europe: Preliminary Results from the European Thoracic Oncology Platform Lungscape Project

, 2012
Fiona Blackhall, Solange Peters, K.M. Kerr, Kenneth J. O’Byrne, Henrik Hager, Aleksandra Sejda, Alex Soltermann, Christophe Dooms, Enriqueta Felip, Antonella Marchetti, Ernst‐Jan M. Speel, Noah Waterfield Price, Sinisa Savic, Jeroen de Jong, Miguel Martorell, Erik Thunnissen, Lukas Bubendorf, O. Dafni, R. Rosell, R. Stahel   +19 more
openalex   +1 more source

New chromosome abnormalities and lack of BCL‐6 gene rearrangements in Argentinean diffuse large B‐cell lymphomas [PDF]

, 2006
Roxana Cerretini, María Fernanda Noriega, Marina Narbaitz, Irma Slavutsky   +3 more
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source