Results 191 to 200 of about 261,418 (285)

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Mitochondrial Genomes of Four Millipedes (Diplopoda: Spirostreptida and Spirobolida) Unveil Phylogenetic Novelty and Gene Rearrangement Patterns. [PDF]

Curr Issues Mol Biol
Li Y, Zhang G, Xu W, Xu T, Li L, Gao M, Wang J, Liu H.   +7 more
europepmc   +1 more source

Comparison of Mitochondrial Genome Sequences between Two Palaemon Species of the Family Palaemonidae (Decapoda: Caridea): Gene Rearrangement and Phylogenetic Implications. [PDF]

Genes (Basel), 2023
Sun Y, Chen J, Ye Y, Xu K, Li J.
europepmc   +1 more source

The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse.

, 1982
Takao Kataoka, T Nikaido, Takashi Miyata, Kenta Moriwaki, Tasuku Honjo   +4 more
openalex   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

Comparative Analysis of <i>Metopograpsus quadridentatus</i> (Crustacea: Decapoda: Grapsidae) Mitochondrial Genome Reveals Gene Rearrangement and Phylogeny. [PDF]

Animals (Basel)
Bian DD, Tang S, Wang SN, Liu QN, Tang BP.   +4 more
europepmc   +1 more source

Expanded Access Program Pralsetinib in Advanced Non-Small Cell Lung Cancer with Rearranged during Transfection (RET) Gene Rearrangement. [PDF]

Cancer Res Treat, 2023
Jeon Y, Jung HA, Park S, Sun JM, Ahn JS, Ahn MJ, Park K, Lee SH.   +7 more
europepmc   +1 more source

Aberrant immunoglobulin and c-myc gene rearrangements in patients with nonmalignant monoclonal cryoglobulinemia. [PDF]

, 1987
András Perl, N Wang, J M Williams, Marjory Hunt, S I Rosenfeld, John J. Condemi, Charles H. Packman, G N Abraham   +7 more
openalex   +1 more source

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

Advanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio‐Lopez, Douglas Hazel, Michael Levin   +6 more
wiley   +1 more source

Characterization of Acute Myeloid Leukemia With RUNX1/RUNX1T1 Gene Rearrangement: Clinical, Hematological, and Morphological Features. [PDF]

Cureus
Maqbool S, Maqbool I, Yousaf M, Farooqi B, Sikandar MZ, Zainab R, Bakht K, Shahid M.   +7 more
europepmc   +1 more source