Results 241 to 250 of about 271,468 (359)

A novel ETV6::FGFR1 fusion gene in a myeloid/lymphoid neoplasm with FGFR1 rearrangement sensitive to specific FGFR1-2-3 inhibition

open access: green, 2023
Carlos Jiménez‐Vicente   +14 more
openalex   +2 more sources

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue   +13 more
wiley   +1 more source

Ki67 deficiency impedes chromatin accessibility and BCR gene rearrangement. [PDF]

open access: yesJ Exp Med
Ding Z   +16 more
europepmc   +1 more source

Comparative Aspects of Immunoglobulin Gene Rearrangement Arrays in Different Species. [PDF]

open access: yesFront Immunol, 2022
Sinkora M   +5 more
europepmc   +1 more source

SV2B Promotes the Progression of TFE3‐Rearranged Renal Cell Carcinoma by Interacting with HERC2 to Impede the Degradation of NF‐κB Subunits

open access: yesAdvanced Science, EarlyView.
TFE3‐rearranged renal cell carcinoma (TFE3‐RCC) lacks clearly defined diagnostic and therapeutic targets. SV2B, a TFE3 target gene, promotes TFE3‐RCC progression by activating the NF‐κB pathway. Targeted inhibition with padsevonil or Withaferin A effectively suppresses tumor progression.
Huayi Feng   +13 more
wiley   +1 more source

Identification and Characterization of a Novel <i>CCDC6::CASP7</i> Gene Rearrangement in an Advanced Colorectal Cancer Patient: A Case Report. [PDF]

open access: yesInt J Mol Sci
Montero JC   +7 more
europepmc   +1 more source

HTGTS‐TCR‐Seq for Profiling of Mouse and Human T‐Cell Receptor α and β Gene Rearrangements and Diversity

open access: yesAdvanced Science, EarlyView.
HTGTS‐TCR‐seq is an efficient and cost‐effective method for profiling TCRα and TCRβ rearrangements using only a few primers. It captures both productive and nonproductive recombination events, minimizes primer bias, and reveals stage‐specific and age‐related repertoire changes in mice, as well as conserved features in human peripheral T cells ...
Rui Luo   +9 more
wiley   +1 more source

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