Results 271 to 280 of about 264,764 (308)

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

Tissue-Matched IgH Gene Rearrangement of Circulating Tumor DNA Shows Significant Value in Predicting the Progression of Diffuse Large B Cell Lymphoma. [PDF]

Oncologist
Zhao K, Zheng X, Liu X, Liu T, Ke Z, Zhu F, Wen Q, Xin B, Li Q, Zhang L.   +9 more
europepmc   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Clinical significance of bone marrow involvement by immunoglobulin gene rearrangement in de novo diffuse large B-cell lymphoma: a multicenter retrospective study. [PDF]

Front Oncol
Kim YR, Shin HJ, Yhim HY, Yang DH, Park Y, Lee JH, Lee WS, Do YR, Mun YC, Kim DS, Kim JS.   +10 more
europepmc   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

Advanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications

American Journal of Hematology, EarlyView.
Robert T. Means Jr
wiley   +1 more source

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Antigen receptor gene rearrangement

Current Opinion in Immunology, 1998
Two specialized forms of site-directed double-strand (ds) DNA breakage and rejoining are part of the physiologic program of lymphocytes. One is recombination of the V, D and J gene sequences, termed V(D)J recombination, occurring during early B- and T-cell development, and the other is class-switch recombination occurring exclusively in mature B cells.
U, Grawunder, R B, West, M R, Lieber
openaire   +2 more sources

Gene Rearrangements Testing

2012
The B- and T-cell gene rearrangement test is one of the hallmarks of the molecular pathology diagnostic laboratories. Historically done with Southern blot and now adopted by many laboratories using PCR, the test is used as an aid in pathology diagnosis to distinguish between benign lymphoproliferative disorders, usually polyclonal, and clonally derived
Siby Sebastian, Juan Du, Rizwan Naeem
openaire   +1 more source

Rearrangement of immunoglobulin genes

Biochemistry, 1979
Wilson, R, Miller, J, Storb, U
openaire   +2 more sources

Gene rearrangement

The Journal of Steroid Biochemistry and Molecular Biology, 1992
openaire   +1 more source