Results 261 to 270 of about 6,256,288 (301)
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Cellular and Molecular Life Sciences (CMLS), 1999
A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for ...
Y, Liu +3 more
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A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for ...
Y, Liu +3 more
openaire +2 more sources
Gene Regulation in Spermatogenesis
2005Mammalian spermatogenesis is a complex hormone-dependent developmental program in which a myriad of events must take place to ensure that germ cells reach their proper stage of development at the proper time. Many of these events are controlled by cell type- and stage-specific transcription factors.
James A, Maclean, Miles F, Wilkinson
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Carotenoids and Gene Regulation
Nutrition Reviews, 2009Consumption of dietary carotenoids, plant pigments found in green, yellow, and orange fruits and vegetables, has been linked to decreased risk of cancer. Several intervention trials with beta-carotene, however, have failed to confirm this association. Indeed, in current smokers, beta-carotene appeared to increase risk. These disturbing results have not
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2016
Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells ...
Ludivine, Breger +3 more
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Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells ...
Ludivine, Breger +3 more
openaire +2 more sources
Gene regulation: Stochastic and deterministic effects in gene regulation
Heredity, 2007J R, Edwards, T H, Bestor
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British Medical Bulletin, 1991
A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
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A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
openaire +2 more sources
Annals of the New York Academy of Sciences, 2000
Abstract: The physiological and neuroendocrine functions of the pineal gland hormone, melatonin, and its therapeutic potential critically depend on the understanding of its target sites and its mechanisms of action. This has progressed considerably in the last few years through the cloning of G protein‐coupled seven‐transmembrane melatonin receptors ...
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Abstract: The physiological and neuroendocrine functions of the pineal gland hormone, melatonin, and its therapeutic potential critically depend on the understanding of its target sites and its mechanisms of action. This has progressed considerably in the last few years through the cloning of G protein‐coupled seven‐transmembrane melatonin receptors ...
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Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases
Cell, 2021Hajime Yoshifuji +2 more
exaly
Regulating Gene Regulation: Patenting Small RNAs
2012Joly, Pierre Benoit +2 more
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Gene regulation in time and space during X-chromosome inactivation
Nature Reviews Molecular Cell Biology, 2022Edith Heard +2 more
exaly