Results 41 to 50 of about 4,429,101 (170)

Genome-Wide Footprints of Pig Domestication and Selection Revealed through Massive Parallel Sequencing of Pooled DNA [PDF]

, 2011
Background Artificial selection has caused rapid evolution in domesticated species. The identification of selection footprints across domesticated genomes can contribute to uncover the genetic basis of phenotypic diversity.
Perez-Enciso, M., Schook, L.B., Nie, H., Crooijmans, R.P.M.A., Groenen, M.A.M., Ferretti, L., Amaral, A.J., Megens, H.J.W.C., Ramos-Onsins, S.E.   +8 more
core   +1 more source

Multidisciplinary therapy strategy of precision medicine in clinical practice

Clinical and Translational Medicine, 2020
The application of precision medicine concept in clinical work needs a period of practice and experience accumulation. The present article introduced an example of functioning approach named “multidisciplinary therapy strategy of precision medicine ...
Mengjia Qian, Qian Li, Miaomiao Zhang, Xiaojing Xu, Qi Shen, Hao Chen, Xiangdong Wang, Tianshu Liu, Yunfeng Cheng   +8 more
doaj   +1 more source

Long-Range Chromosomal Mapping of the Carcinoembryonic Antigen (CEA) Gene Family Cluster [PDF]

, 1992
A long-range physical map of the carcinoembryonic antigen (CEA) gene family cluster, which is located on the long arm of chromosome 19, has been constructed.
Barnert, Sabine, Zimmermann, Wolfgang, Eades-Perner, Anne-Marie, Osthus-Bugat, P., Craig, Ian, Schleussner, Cathrin, Willcocks, Teresa, Mohrenweiser, Harvey, Tynan, Katherine, Thompson, John A., Olsen, Anne, I. Craig, T. Willcocks, C. Schleussner, S. Von Kleist, K. Tynan, J. Thompson, P. Osthus-Bugat, H. Mohrenweiser, A.-M. Eades-Perner, S. Barnert, A. Olsen, W. Zimmermann   +22 more
core   +1 more source

Evaluation of sample pooling for gene sequencing of SARS-CoV-2: a simulation study

Journal of Infection in Developing Countries
Introduction: Coronavirus disease 2019 (COVID-19) continues to pose a significant public health threat, requiring epidemiological and genomic surveillance.
Heng Chen, Yue Cheng, Xun He, Yuzhen Zhou, Wenjun Xie, Danyun Shen, Zhiqun He, Ruidan Li, Weixuan Liu, Liang Wang, Xuejun Zhang   +10 more
doaj   +1 more source

High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing [PDF]

, 2012
BACKGROUND: Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod ...
Spooner Paul R, Ulrich Certa, Pelle, R., Richard P Bishop, Ebeling, M., Pelle Roger, Lucy Poveda, Roger Pelle, Küng, Erich, Morzaria, S., Henson, Sonal, Morzaria, S.P., Erich Küng, Bishop, Richard P., Daubenberger, C.A., Daubenberger, Claudia A., Certa, U., Spooner, Paul R, Poveda, Lucy, Paul R Spooner, Poveda, L., Ebeling, Martin, Certa, Ulrich, Claudia A Daubenberger, Spooner, P.R., Weihong Qi, Sonal Henson, Bishop Richard P, Spooner, Paul R., Certa Ulrich, Henson Sonal, Henson, S., Morzaria Subhash, Qi Weihong, Poveda Lucy, Subhash Morzaria, Bishop, R. P., Spooner, P. R., Kung, E., Pelle, Roger, Ebeling Martin, Küng Erich, Daubenberger Claudia A, Morzaria, Subhash, Daubenberger, C. A., Bishop, Richard P, Martin Ebeling, Qi, W., Qi, Weihong, Daubenberger, Claudia A   +49 more
core   +1 more source

Next Generation Sequencing (Dagstuhl Seminar 16351)

, 2017
Next Generation Sequencing (NGS) data have begun to appear in many applications that are clinically relevant, such as resequencing of cancer patients, disease-gene discovery and diagnostics for rare diseases, microbiome analyses, and gene expression ...
Pop, Mihai, Meyers, Gene, Reinert, Knut, Warnow, Tandy, Myers, Gene   +4 more
core   +1 more source

Short read Illumina data for the de novo assembly of a non-model snail species transcriptome (Radix balthica, Basommatophora, Pulmonata), and a comparison of assembler performance [PDF]

, 2011
Background: Until recently, read lengths on the Solexa/Illumina system were too short to reliably assemble transcriptomes without a reference sequence, especially for non-model organisms.
Wheat, Christopher W., Markus Pfenninger, Rotter, Björn, Pfenninger, Markus, Björn Rotter, Christopher W Wheat, Nicolas Krezdorn, Feldmeyer, Barbara, Krezdorn, Nicolas, Rotter, Bjoern, Barbara Feldmeyer   +10 more
core   +2 more sources

Comparison of 16S rRNA Sequencing and VITEK 2 Analysis for the Identification of Acinetobacter baumannii Clinical Isolates: A Study from Southwestern Province of Saudi Arabia [PDF]

Journal of Clinical and Diagnostic Research
Acinetobacter baumannii (A. baumannii) is one of the major causes of nosocomial infections in the hospital environment. Even the World Health Organisation (WHO) has designated A.
Vinod Kumar Basode, Ahmed Abdulhaq, Nader Kameli, Mohammed Uthman A Alamoudi, A Abu Alsayl Zuhair Hussain   +4 more
doaj   +1 more source

Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples. [PDF]

, 2012
peer-reviewedBackground: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an ...
Magee, David A, Mullen Michael P, Creevey Christopher J, Park, Stephen D, Killeen Aideen P, Donagh P Berry, Killeen, Aideen P, Park Stephen D, Howard, Dawn J, McGettigan, Paul A., Christopher J Creevey, Creevey, Christopher J.; id_orcid, Matt C Lucy, Michael P Mullen, Waters, Sinead M., Howard Dawn J, David A Magee, Howard, Dawn J., Lucy Matt C, Mullen, Michael P, Berry Donagh P, Berry, Donagh P., McCabe, Matt S., Park, Stephen D., Magee, David A., McCabe Matt S, Dawn J Howard, Creevey, Christopher J., Matt S McCabe, Lucy, Matt C., Waters, Sinead M, McCabe, Matt S, Killeen, Aideen P., Lucy, Matt C, Magee David A, McGettigan Paul A, Paul A McGettigan, Waters Sinead M, MacHugh, David E, MacHugh David E, David E MacHugh, Aideen P Killeen, MacHugh, David E., Park, Stephen D. E., McGettigan, Paul A, McGettigan, Paul, Mullen, Michael P., McCabe, Matthew, Creevey, Christopher J, Berry, Donagh P, Sinead M Waters, Stephen D Park, Berry, Donagh   +52 more
core   +1 more source

A Genomic Approach to Characterize the Vulnerable Patient – a Clinical Update

Journal of Interdisciplinary Medicine, 2019
Atherosclerosis is the elemental precondition for any cardiovascular disease and the predominant cause of ischemic heart disease that often leads to myocardial infarction.
Szabó Evelin, Parajkó Zsolt, Opincariu Diana, Chițu Monica, Raț Nóra, Benedek Imre   +5 more
doaj   +1 more source